Trait
Laryngeal cleft
Presence of a gap in the posterior laryngotracheal wall with a continuity between the larynx and the esophagus.
Summary
- Also called
- Laryngotracheal cleft, Laryngotracheoesophageal cleft i
- Body system
- Abnormality of the respiratory system
Reference genomeGRCh38hg38
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Get my Genome Test7 genes linked to Laryngeal cleft
Changes in these genes cause rare conditions in which Laryngeal cleft is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| GLI3GLI family zinc finger 3 | Often (30–79%) | In 2 conditions |
| MID1midline 1 | Often (30–79%) | In 2 conditions |
| PHIPPHIP subunit of CUL4-Ring ligase complex | Often (30–79%) | In 1 condition |
| CAPN15calpain 15 | Sometimes (5–29%) | In 1 condition |
| EDN1endothelin 1 | Sometimes (5–29%) | In 1 condition |
| FBXW7F-box and WD repeat domain containing 7 | Rarely (1–4%) | In 1 condition |
| SPTBN1spectrin beta, non-erythrocytic 1 | Rarely (1–4%) | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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