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Gene

TMEM260

transmembrane protein 260

Summary

Cytogenetic location
14q22.3
Coordinates
Chromosome 14: 56,579,798–56,649,515 (GRCh38)
Exons
16 exons across 69.7 kb
Protein
707 amino acids
Also known as
FLJ20392
Previous symbols
C14orf101
MANE Select transcript
ENST00000261556.11NM_017799.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads TMEM260 yet. The test sequences your whole genome, so your data includes it all the same.

How TMEM260 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 14, with a bracket where TMEM260 sits. TMEM260 and 2 genes near it on chromosome 14, from 56,114,657 to 57,114,656.Chromosome 1414q22.3p13p12p11.2p11.1q11.1q11.2q12q13.1q13.2q13.3q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q31.1q31.2q31.3q32.11q32.12q32.13q32.2q32.31q32.32q32.3356.2 Mb56.4 Mb56.6 Mb56.8 Mb57 MbPELI2: 56,117,814–56,301,746, forward strandPELI2TMEM260: 56,579,798–56,649,515, forward strandTMEM260OTX2: 56,799,810–56,816,792, reverse strandOTX2Diagram of TMEM260: 16 exons on the forward strand of chromosome 14Exon 1: 2 known disease-causing sitesExon 3: 3 known disease-causing sitesExon 4: 2 known disease-causing sitesExon 6: 2 known disease-causing sitesExon 8: 1 known disease-causing siteExon 11: 2 known disease-causing sitesExon 12: 3 known disease-causing sitesExon 13: 3 known disease-causing sitesExon 14: 1 known disease-causing siteExon 15: 1 known disease-causing siteExon 16: 1 known disease-causing siteExon 1: 56,579,798–56,580,074, 277 basesExon 2: 56,585,001–56,585,032, 32 basesExon 3: 56,585,761–56,585,912, 152 basesExon 4: 56,603,815–56,603,992, 178 basesExon 5: 56,605,570–56,605,683, 114 basesExon 6: 56,609,106–56,609,285, 180 basesExon 7: 56,612,245–56,612,285, 41 basesExon 8: 56,615,944–56,616,027, 84 basesExon 9: 56,617,183–56,617,297, 115 basesExon 10: 56,618,594–56,618,763, 170 basesExon 11: 56,621,531–56,621,702, 172 basesExon 12: 56,625,382–56,625,530, 149 basesExon 13: 56,632,995–56,633,171, 177 basesExon 14: 56,634,899–56,634,952, 54 basesExon 15: 56,636,508–56,636,598, 91 basesExon 16: 56,647,243–56,649,515, 2,273 bases12468101214165′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 4.3 kb of the gene's 69.7 kb; 2,124 of those bases code for the protein.

How a genome test reads TMEM260

23

positions in TMEM260 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 69.7 kb of TMEM260, introns included, not only the 4.3 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). TMEM260 gene: transmembrane protein 260. Retrieved 17 October 2026, from https://dantelabs.com/genes/tmem260

Vancouver

Dante Labs. TMEM260 gene: transmembrane protein 260 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/tmem260

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