Gene
SLC35B2
solute carrier family 35 member B2
- HGNC 16872↗(opens in a new tab)
- Ensembl gene ENSG00000157593↗(opens in a new tab)
- NCBI Gene 347734↗(opens in a new tab)
Summary
- Cytogenetic location
- 6p21.1
- Coordinates
- Chromosome 6: 44,254,101–44,257,528 (GRCh38)
- Exons
- 4 exons across 3.4 kb
- Protein
- 432 amino acids
- Also known as
- UGTrel4
- MANE Select transcript
- ENST00000393812.4NM_178148.4
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read SLC35B2, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome TestCurated reports relevant to this gene
No Genome Test report reads SLC35B2 yet. The test sequences your whole genome, so your data includes it all the same.
How SLC35B2 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Known disease-causing sites
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 2 kb of the gene's 3.4 kb; 1,299 of those bases code for the protein.
How a genome test reads SLC35B2
2
positions in SLC35B2 where ClinVar classes a change as pathogenic or likely pathogenic
None of them falls in a region short reads find hard.
A whole genome covers all 3.4 kb of SLC35B2, introns included, not only the 2 kb of exons.
Traits linked to SLC35B2
The Human Phenotype Ontology lists these as features of the rare conditions SLC35B2 can cause. Each trait's page lists the other genes linked to it.
Abnormality of the nervous system
- Global developmental delay
- Absent speech development
- Degeneration of cerebellum
- Degeneration of cerebrum
- Delayed CNS myelination
- Leukodystrophy
- Limb dystonia
- Thin corpus callosum
Show 1 more trait
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
Cite this page
Dante Labs. (n.d.). SLC35B2 gene: solute carrier family 35 member B2. Retrieved 17 October 2026, from https://dantelabs.com/genes/slc35b2
Dante Labs. SLC35B2 gene: solute carrier family 35 member B2 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/slc35b2
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks