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Gene

SIPA1L3

signal induced proliferation associated 1 like 3

Summary

Cytogenetic location
19q13.13-q13.2
Coordinates
Chromosome 19: 37,907,208–38,208,369 (GRCh38)
Exons
22 exons across 301.2 kb
Protein
1,781 amino acids
Also known as
KIAA0545, SPAR3
MANE Select transcript
ENST00000222345.11NM_015073.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads SIPA1L3 yet. The test sequences your whole genome, so your data includes it all the same.

How SIPA1L3 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 19, with a bracket where SIPA1L3 sits. SIPA1L3 and 21 genes near it on chromosome 19, from 37,557,789 to 38,557,788.Chromosome 1919q13.13-q13.2p13.3p13.2p13.13p13.12p13.11p12p11q11q12q13.11q13.12q13.13q13.2q13.31q13.32q13.33q13.41q13.42q13.4337.6 Mb37.8 Mb38 Mb38.2 Mb38.4 MbZNF540: 37,551,406–37,614,179, forward strandZNF540ZNF571: 37,554,780–37,595,147, reverse strandZNF571ZFP30: 37,613,645–37,692,337, reverse strandZFP30: 37,689,865–37,719,188, reverse strandZNF607: 37,696,349–37,719,780, reverse strandZNF607ZNF573: 37,735,833–37,817,300, reverse strandZNF573WDR87: 37,884,823–37,906,677, reverse strandWDR87SIPA1L3: 37,907,208–38,208,369, forward strandSIPA1L3DPF1: 38,211,006–38,229,729, reverse strandDPF1SPINT2: 38,244,035–38,292,615, forward strandSPINT2PPP1R14A: 38,250,856–38,256,615, reverse strandPPP1R14A: 38,289,151–38,304,910, forward strandYIF1B: 38,303,558–38,317,273, reverse strandC19orf33: 38,304,158–38,305,011, forward strandC19orf33KCNK6: 38,319,813–38,333,553, forward strandKCNK6CATSPERG: 38,335,775–38,370,943, forward strandCATSPERGPSMD8: 38,374,563–38,383,850, forward strandPSMD8GGN: 38,384,267–38,388,274, reverse strandGGNSPRED3: 38,388,421–38,399,588, forward strandSPRED3TSLIG3C: 38,403,093–38,409,088, forward strandRASGRP4: 38,409,051–38,426,305, reverse strandRYR1: 38,433,691–38,595,273, forward strandRYR1Diagram of SIPA1L3: 22 exons on the forward strand of chromosome 19Exon 12: 1 known disease-causing siteExon 1: 37,907,208–37,907,358, 151 basesExon 2: 38,029,089–38,029,156, 68 basesExon 3: 38,081,256–38,083,099, 1,844 basesExon 4: 38,088,721–38,088,851, 131 basesExon 5: 38,099,962–38,100,150, 189 basesExon 6: 38,101,052–38,101,226, 175 basesExon 7: 38,106,537–38,106,640, 104 basesExon 8: 38,110,227–38,110,384, 158 basesExon 9: 38,119,306–38,119,882, 577 basesExon 10: 38,130,498–38,130,772, 275 basesExon 11: 38,141,184–38,141,435, 252 basesExon 12: 38,142,573–38,142,710, 138 basesExon 13: 38,152,840–38,152,967, 128 basesExon 14: 38,162,253–38,162,371, 119 basesExon 15: 38,164,479–38,164,906, 428 basesExon 16: 38,182,519–38,182,740, 222 basesExon 17: 38,192,145–38,192,310, 166 basesExon 18: 38,193,537–38,193,780, 244 basesExon 19: 38,198,389–38,198,532, 144 basesExon 20: 38,201,862–38,201,997, 136 basesExon 21: 38,204,127–38,204,208, 82 basesExon 22: 38,206,097–38,208,369, 2,273 bases1225′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 8 kb of the gene's 301.2 kb; 5,346 of those bases code for the protein.

How a genome test reads SIPA1L3

1

position in SIPA1L3 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 301.2 kb of SIPA1L3, introns included, not only the 8 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). SIPA1L3 gene: signal induced proliferation associated 1 like 3. Retrieved 17 October 2026, from https://dantelabs.com/genes/sipa1l3

Vancouver

Dante Labs. SIPA1L3 gene: signal induced proliferation associated 1 like 3 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/sipa1l3

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