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Gene

MDH1

malate dehydrogenase 1

Summary

Cytogenetic location
2p15
Coordinates
Chromosome 2: 63,588,963–63,607,197 (GRCh38)
Exons
9 exons across 18.2 kb
Protein
334 amino acids
MANE Select transcript
ENST00000233114.13NM_005917.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads MDH1 yet. The test sequences your whole genome, so your data includes it all the same.

How MDH1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 2, with a bracket where MDH1 sits. MDH1 and 4 genes near it on chromosome 2, from 63,098,080 to 64,098,079.Chromosome 22p15p25.3p25.2p25.1p24.3p24.2p24.1p23.3p23.2p23.1p22.3p22.2p22.1p21p16.3p16.2p16.1p15p14p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12.1q12.2q12.3q13q14.1q14.2q14.3q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q31.1q31.2q31.3q32.1q32.2q32.3q33.1q33.2q33.3q34q35q36.1q36.2q36.3q37.1q37.2q37.363.2 Mb63.4 Mb63.6 Mb63.8 Mb64 MbWDPCP: 63,119,559–63,827,843, reverse strandWDPCPMDH1: 63,588,963–63,607,197, forward strandMDH1UGP2: 63,840,945–63,951,431, forward strandUGP2VPS54: 63,891,701–64,019,550, reverse strandVPS54PELI1: 64,092,543–64,144,473, reverse strandPELI1Diagram of MDH1: 9 exons on the forward strand of chromosome 2Exon 1: 63,588,963–63,589,046, 84 basesExon 2: 63,594,488–63,594,586, 99 basesExon 3: 63,595,423–63,595,519, 97 basesExon 4: 63,597,399–63,597,574, 176 basesExon 5: 63,599,170–63,599,292, 123 basesExon 6: 63,604,696–63,604,872, 177 basesExon 7: 63,605,280–63,605,393, 114 basesExon 8: 63,605,939–63,606,028, 90 basesExon 9: 63,606,862–63,607,197, 336 bases1234567895′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.3 kb of the gene's 18.2 kb; 1,005 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.

Cite this page

APA

Dante Labs. (n.d.). MDH1 gene: malate dehydrogenase 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/mdh1

Vancouver

Dante Labs. MDH1 gene: malate dehydrogenase 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/mdh1

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