Traits

Traits linked to F7

coagulation factor VII

The Human Phenotype Ontology links 16 traits to F7, by body system: features seen in people with one of the gene's rare conditions.

Abnormality of blood and blood-forming tissues

Trait	How often it is seen
Abnormally heavy bleeding during menstruation	Always
Bleeding within a joint	Always
Bloody nose	Always
Bruising susceptibility	Always
Prolonged bleeding after dental extraction	Always
Reduced factor VII activity	Always
Bleeding within the skull	Very often (80–99%)
Gastrointestinal bleeding	Very often (80–99%)
Bleeding gums	Often (30–79%)
Prolonged bleeding after surgery	Often (30–79%)
Prolonged prothrombin time	Often (30–79%)
Bleeding post-delivery	Sometimes (5–29%)
Bleeding tendency	Not recorded

Abnormality of prenatal development or birth

Trait	How often it is seen
Umbilical cord issue	Sometimes (5–29%)

Abnormality of the genitourinary system

Trait	How often it is seen
Ovarian cyst	Sometimes (5–29%)

Abnormality of the musculoskeletal system

Trait	How often it is seen
Intramuscular hematoma	Not recorded

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the traits linked to F7 and how often each is seen. Find out more at hpo.jax.org.

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