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Gene

CCDC146

coiled-coil domain containing 146

Summary

Cytogenetic location
7q11.23
Coordinates
Chromosome 7: 77,122,615–77,295,204 (GRCh38)
Exons
19 exons across 172.6 kb
Protein
955 amino acids
Also known as
KIAA1505, MBO2
MANE Select transcript
ENST00000285871.5NM_020879.3
Locus type
Protein-coding
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads CCDC146 yet. The test sequences your whole genome, so your data includes it all the same.

How CCDC146 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 7, with a bracket where CCDC146 sits. CCDC146 and 6 genes near it on chromosome 7, from 76,708,910 to 77,708,909.Chromosome 77q11.23p22.3p22.2p22.1p21.3p21.2p21.1p15.3p15.2p15.1p14.3p14.2p14.1p13p12.3p12.2p12.1p11.2p11.1q11.1q11.21q11.22q11.23q21.11q21.12q21.13q21.2q21.3q22.1q22.2q22.3q31.1q31.2q31.31q31.32q31.33q32.1q32.2q32.3q33q34q35q36.1q36.2q36.376.8 Mb77 Mb77.2 Mb77.4 Mb77.6 MbSPDYE17: 77,022,306–77,032,361, reverse strandSPDYE17SPDYE18: 77,050,391–77,063,938, reverse strandSPDYE18CCDC146: 77,122,615–77,295,204, forward strandCCDC146FGL2: 77,193,182–77,199,884, reverse strandFGL2GSAP: 77,310,483–77,416,607, reverse strandGSAPPTPN12: 77,537,065–77,640,072, forward strandPTPN12RSBN1L: 77,696,440–77,783,022, forward strandRSBN1LDiagram of CCDC146: 19 exons on the forward strand of chromosome 7Exon 6: 1 known disease-causing siteExon 8: 1 known disease-causing siteExon 1: 77,122,615–77,122,732, 118 basesExon 2: 77,167,658–77,167,824, 167 basesExon 3: 77,236,947–77,237,029, 83 basesExon 4: 77,241,691–77,241,900, 210 basesExon 5: 77,254,506–77,254,563, 58 basesExon 6: 77,256,333–77,256,509, 177 basesExon 7: 77,258,995–77,259,068, 74 basesExon 8: 77,260,009–77,260,236, 228 basesExon 9: 77,262,121–77,262,307, 187 basesExon 10: 77,273,694–77,273,789, 96 basesExon 11: 77,274,482–77,274,652, 171 basesExon 12: 77,278,752–77,278,840, 89 basesExon 13: 77,278,937–77,279,101, 165 basesExon 14: 77,280,429–77,280,653, 225 basesExon 15: 77,282,557–77,282,785, 229 basesExon 16: 77,286,798–77,286,926, 129 basesExon 17: 77,287,440–77,287,577, 138 basesExon 18: 77,292,952–77,293,200, 249 basesExon 19: 77,294,663–77,295,204, 542 bases151015195′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.3 kb of the gene's 172.6 kb; 2,868 of those bases code for the protein.

Sequencing CCDC146

3

positions in CCDC146 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 172.6 kb of CCDC146, introns included, not only the 3.3 kb of exons.

Traits linked to CCDC146

The Human Phenotype Ontology lists these as features of the rare conditions CCDC146 can cause. Each trait's page lists the other genes linked to it.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.17-8666dff2.

Cite this page

APA

Dante Labs. (n.d.). CCDC146 gene: coiled-coil domain containing 146. Retrieved 17 October 2026, from https://dantelabs.com/genes/ccdc146

Vancouver

Dante Labs. CCDC146 gene: coiled-coil domain containing 146 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/ccdc146

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