Skip to content
Use your HSA or FSA funds
Sequence your genome (opens in a new tab)

Gene

PTPN12

protein tyrosine phosphatase non-receptor type 12

Summary

Cytogenetic location
7q11.23
Coordinates
Chromosome 7: 77,537,295–77,640,069 (GRCh38)
Exons
18 exons across 102.8 kb
Protein
780 amino acids
Also known as
PTPG1, PTP-PEST
MANE Select transcript
ENST00000248594.11NM_002835.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads PTPN12 yet. The test sequences your whole genome, so your data includes it all the same.

How PTPN12 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 7, with a bracket where PTPN12 sits. PTPN12 and 7 genes near it on chromosome 7, from 77,088,682 to 78,088,681.Chromosome 77q11.23p22.3p22.2p22.1p21.3p21.2p21.1p15.3p15.2p15.1p14.3p14.2p14.1p13p12.3p12.2p12.1p11.2p11.1q11.1q11.21q11.22q11.23q21.11q21.12q21.13q21.2q21.3q22.1q22.2q22.3q31.1q31.2q31.31q31.32q31.33q32.1q32.2q32.3q33q34q35q36.1q36.2q36.377.2 Mb77.4 Mb77.6 Mb77.8 Mb78 MbCCDC146: 77,122,434–77,329,533, forward strandCCDC146FGL2: 77,193,182–77,199,884, reverse strandFGL2GSAP: 77,310,483–77,416,607, reverse strandGSAPPTPN12: 77,537,295–77,640,069, forward strandPTPN12RSBN1L: 77,696,440–77,783,022, forward strandRSBN1LTMEM60: 77,793,728–77,799,723, reverse strandTMEM60PHTF2: 77,798,652–77,957,503, forward strandPHTF2MAGI2: 78,017,055–79,453,845, reverse strandMAGI2Diagram of PTPN12: 18 exons on the forward strand of chromosome 7Exon 1: 77,537,295–77,537,645, 351 basesExon 2: 77,571,078–77,571,186, 109 basesExon 3: 77,581,427–77,581,503, 77 basesExon 4: 77,583,555–77,583,650, 96 basesExon 5: 77,585,543–77,585,581, 39 basesExon 6: 77,592,185–77,592,256, 72 basesExon 7: 77,597,842–77,597,901, 60 basesExon 8: 77,600,664–77,600,806, 143 basesExon 9: 77,607,235–77,607,301, 67 basesExon 10: 77,610,765–77,610,842, 78 basesExon 11: 77,610,948–77,611,046, 99 basesExon 12: 77,618,480–77,618,565, 86 basesExon 13: 77,626,705–77,627,675, 971 basesExon 14: 77,632,348–77,632,425, 78 basesExon 15: 77,635,782–77,635,849, 68 basesExon 16: 77,637,018–77,637,048, 31 basesExon 17: 77,638,624–77,638,731, 108 basesExon 18: 77,639,219–77,640,069, 851 bases1246810121416185′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.4 kb of the gene's 102.8 kb; 2,343 of those bases code for the protein.

Traits linked to PTPN12

The Human Phenotype Ontology lists these as features of the rare conditions PTPN12 can cause. Each trait's page lists the other genes linked to it.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.

Cite this page

APA

Dante Labs. (n.d.). PTPN12 gene: protein tyrosine phosphatase non-receptor type 12. Retrieved 17 October 2026, from https://dantelabs.com/genes/ptpn12

Vancouver

Dante Labs. PTPN12 gene: protein tyrosine phosphatase non-receptor type 12 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/ptpn12

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test