Traits

Traits linked to CALM2

calmodulin 2

The Human Phenotype Ontology links 12 traits to CALM2, by body system: features seen in people with one of the gene's rare conditions.

Abnormality of the cardiovascular system

Trait	How often it is seen
2:1 atrioventricular block	Always
Prolonged QTc interval	Always
Sinus bradycardia	Always
Fainting spell	Very often (80–99%)
Extra heart beat	Often (30–79%)
Heart stops beating	Often (30–79%)
Slow heartbeats	Often (30–79%)
Ventricular fibrillation	Often (30–79%)
Left ventricular noncompaction	Sometimes (5–29%)
Polymorphic ventricular tachycardia	Sometimes (5–29%)
Ventricular bigeminy	Sometimes (5–29%)

Abnormality of the nervous system

Trait	How often it is seen
Epilepsy	Sometimes (5–29%)

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the traits linked to CALM2 and how often each is seen. Find out more at hpo.jax.org.

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