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Trait

2:1 atrioventricular block

A type of second-degree atrioventricular block in which every other P wave is not conducted through the AV node such that only every other P wave is followed by a QRS complex.

HPO HP:0034305

Summary

Also called
2:1 AV block
Body system
Abnormality of the cardiovascular system

3 genes linked to 2:1 atrioventricular block

Changes in these genes cause rare conditions in which 2:1 atrioventricular block is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

GeneHow often it is seenConditions
CALM2calmodulin 2AlwaysIn 1 condition
CALM1calmodulin 1Often (30–79%)In 1 condition
POPDC2popeye domain cAMP effector 2Often (30–79%)In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Second degree atrioventricular block

Where this comes from

  • The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

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