Skip to content
Use your HSA or FSA funds

Gene

A2ML1

alpha-2-macroglobulin like 1

Summary

Cytogenetic location
12p13.31
Coordinates
Chromosome 12: 8,822,621–8,876,787 (GRCh38)
Exons
36 exons across 54.2 kb
Protein
1,454 amino acids
Also known as
FLJ25179, p170
Previous symbols
CPAMD9
MANE Select transcript
ENST00000299698.12NM_144670.6
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads A2ML1 yet. The test sequences your whole genome, so your data includes it all the same.

How A2ML1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 12, with a bracket where A2ML1 sits. A2ML1 and 11 genes near it on chromosome 12, from 8,349,704 to 9,349,703.Chromosome 1212p13.31p13.33p13.32p13.31p13.2p13.1p12.3p12.2p12.1p11.23p11.22p11.21p11.1q11q12q13.11q13.12q13.13q13.2q13.3q14.1q14.2q14.3q15q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.11q24.12q24.13q24.21q24.22q24.23q24.31q24.32q24.338.4 Mb8.6 Mb8.8 Mb9 Mb9.2 MbCLEC6A: 8,455,950–8,479,779, forward strandCLEC6ACLEC4D: 8,509,475–8,522,641, forward strandCLEC4DCLEC4E: 8,533,273–8,541,079, reverse strandCLEC4EAICDA: 8,602,155–8,613,242, reverse strandAICDAMFAP5: 8,637,346–8,672,519, reverse strandMFAP5RIMKLB: 8,681,483–8,783,095, forward strandRIMKLBA2ML1: 8,822,621–8,876,787, forward strandA2ML1PHC1: 8,913,824–8,944,860, forward strandPHC1M6PR: 8,940,358–8,951,856, reverse strandM6PRKLRG1: 8,950,044–9,165,627, forward strandKLRG1A2M: 9,067,664–9,116,229, reverse strandA2MPZP: 9,148,840–9,208,410, reverse strandPZPDiagram of A2ML1: 36 exons on the forward strand of chromosome 12Exon 1: 1 known disease-causing siteExon 1: 8,822,621–8,822,713, 93 basesExon 2: 8,823,182–8,823,365, 184 basesExon 3: 8,823,720–8,823,882, 163 basesExon 4: 8,829,727–8,829,779, 53 basesExon 5: 8,834,662–8,834,682, 21 basesExon 6: 8,835,507–8,835,666, 160 basesExon 7: 8,836,255–8,836,339, 85 basesExon 8: 8,837,440–8,837,566, 127 basesExon 9: 8,838,336–8,838,450, 115 basesExon 10: 8,839,113–8,839,222, 110 basesExon 11: 8,841,369–8,841,536, 168 basesExon 12: 8,843,134–8,843,361, 228 basesExon 13: 8,845,442–8,845,502, 61 basesExon 14: 8,846,077–8,846,222, 146 basesExon 15: 8,847,549–8,847,698, 150 basesExon 16: 8,848,720–8,848,914, 195 basesExon 17: 8,849,669–8,849,759, 91 basesExon 18: 8,850,160–8,850,274, 115 basesExon 19: 8,851,784–8,852,012, 229 basesExon 20: 8,852,210–8,852,336, 127 basesExon 21: 8,854,128–8,854,249, 122 basesExon 22: 8,854,780–8,854,831, 52 basesExon 23: 8,855,509–8,855,592, 84 basesExon 24: 8,857,164–8,857,340, 177 basesExon 25: 8,857,507–8,857,588, 82 basesExon 26: 8,857,946–8,858,102, 157 basesExon 27: 8,860,881–8,860,955, 75 basesExon 28: 8,861,135–8,861,297, 163 basesExon 29: 8,863,794–8,864,008, 215 basesExon 30: 8,867,842–8,868,057, 216 basesExon 31: 8,868,230–8,868,357, 128 basesExon 32: 8,868,537–8,868,627, 91 basesExon 33: 8,869,135–8,869,203, 69 basesExon 34: 8,874,425–8,874,527, 103 basesExon 35: 8,874,971–8,875,012, 42 basesExon 36: 8,876,058–8,876,787, 730 bases15101520253035365′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 5.1 kb of the gene's 54.2 kb; 4,365 of those bases code for the protein.

How a genome test reads A2ML1

2

positions in A2ML1 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 54.2 kb of A2ML1, introns included, not only the 5.1 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). A2ML1 gene: alpha-2-macroglobulin like 1. Retrieved 16 October 2026, from https://dantelabs.com/genes/a2ml1

Vancouver

Dante Labs. A2ML1 gene: alpha-2-macroglobulin like 1 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/a2ml1

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test