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Trait

Ventricular escape rhythm

A ventricular escape rhythm occurs whenever higher-lever pacemakers in AV junction or sinus node fail to control ventricular activation. Escape rate is usually 20-40 bpm, often associated with broad QRS complexes (at least 120 ms).

HPO HP:0005155

Summary

Also called
Idioventricular escape rhythm
Body system
Abnormality of the cardiovascular system

11 genes linked to Ventricular escape rhythm

Changes in these genes cause rare conditions in which Ventricular escape rhythm is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

GeneHow often it is seenConditions
EMDemerinAlwaysIn 2 conditions
GJA5gap junction protein alpha 5AlwaysIn 1 condition
NPPAnatriuretic peptide AVery often (80–99%)In 1 condition
SCN5Asodium voltage-gated channel alpha subunit 5Very often (80–99%)In 2 conditions
GNB5G protein subunit beta 5Often (30–79%)In 1 condition
LMNAlamin A/COften (30–79%)In 2 conditions
SGO1shugoshin 1Sometimes (5–29%)In 1 condition
FHL1four and a half LIM domains 1Rarely (1–4%)In 1 condition
SYNE1spectrin repeat containing nuclear envelope protein 1Rarely (1–4%)In 1 condition
SYNE2spectrin repeat containing nuclear envelope protein 2Rarely (1–4%)In 1 condition
TMEM43transmembrane protein 43Rarely (1–4%)In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Ventricular arrhythmia

Where this comes from

  • The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
  • Data release 2026.10.17-8666dff2.

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