Trait
Lichenification
Thickening and hardening of the epidermis seen with exaggeration of normal skin lines.
Summary
- Body system
- Abnormality of the integument
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Get my Genome Test12 genes linked to Lichenification
Changes in these genes cause rare conditions in which Lichenification is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| OSMRoncostatin M receptor | Always | In 1 condition |
| CD28CD28 molecule | Very often (80–99%) | In 1 condition |
| CTLA4cytotoxic T-lymphocyte associated protein 4 | Very often (80–99%) | In 1 condition |
| SPINK5serine peptidase inhibitor Kazal type 5 | Very often (80–99%) | In 1 condition |
| TNFRSF1BTNF receptor superfamily member 1B | Very often (80–99%) | In 1 condition |
| COL7A1collagen type VII alpha 1 chain | Often (30–79%) | In 1 condition |
| HLA-DRAmajor histocompatibility complex, class II, DR alpha | Often (30–79%) | In 1 condition |
| NTRK1neurotrophic receptor tyrosine kinase 1 | Often (30–79%) | In 2 conditions |
| CARD14caspase recruitment domain family member 14 | Sometimes (5–29%) | In 1 condition |
| FLT4fms related receptor tyrosine kinase 4 | Sometimes (5–29%) | In 1 condition |
| LBRlamin B receptor | Sometimes (5–29%) | In 1 condition |
| CSTAcystatin A | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
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Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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