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Gene

SPIDR

scaffold protein involved in DNA repair

Summary

Cytogenetic location
8q11.21
Coordinates
Chromosome 8: 47,260,938–47,736,306 (GRCh38)
Exons
20 exons across 475.4 kb
Protein
915 amino acids
Previous symbols
KIAA0146
MANE Select transcript
ENST00000297423.9NM_001080394.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads SPIDR yet. The test sequences your whole genome, so your data includes it all the same.

How SPIDR is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 8, with a bracket where SPIDR sits. SPIDR and 4 genes near it on chromosome 8, from 46,785,569 to 48,211,675.Chromosome 88q11.21p23.3p23.2p23.1p22p21.3p21.2p21.1p12p11.23p11.22p11.21p11.1q11.1q11.21q11.22q11.23q12.1q12.2q12.3q13.1q13.2q13.3q21.11q21.12q21.13q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.11q24.12q24.13q24.21q24.22q24.23q24.346.8 Mb47 Mb47.2 Mb47.4 Mb47.6 Mb47.8 Mb48 Mb48.2 MbSPIDR: 47,260,938–47,736,306, forward strandSPIDRCEBPD: 47,735,634–47,738,164, reverse strandCEBPDPRKDC: 47,772,970–47,960,182, reverse strandPRKDCMCM4: 47,960,185–47,979,181, forward strandMCM4UBE2V2: 48,008,410–48,067,523, forward strandUBE2V2Diagram of SPIDR: 20 exons on the forward strand of chromosome 8Exon 8: 1 known disease-causing siteExon 12: 1 known disease-causing siteExon 15: 1 known disease-causing siteExon 1: 47,260,938–47,260,991, 54 basesExon 2: 47,279,862–47,280,017, 156 basesExon 3: 47,284,028–47,284,094, 67 basesExon 4: 47,291,033–47,291,137, 105 basesExon 5: 47,293,867–47,294,030, 164 basesExon 6: 47,396,376–47,396,626, 251 basesExon 7: 47,407,861–47,407,961, 101 basesExon 8: 47,440,323–47,440,542, 220 basesExon 9: 47,595,811–47,596,006, 196 basesExon 10: 47,598,946–47,599,196, 251 basesExon 11: 47,673,801–47,673,941, 141 basesExon 12: 47,700,403–47,700,490, 88 basesExon 13: 47,701,721–47,701,864, 144 basesExon 14: 47,701,956–47,702,015, 60 basesExon 15: 47,712,662–47,712,872, 211 basesExon 16: 47,713,489–47,713,641, 153 basesExon 17: 47,727,200–47,727,293, 94 basesExon 18: 47,728,933–47,729,047, 115 basesExon 19: 47,729,412–47,729,465, 54 basesExon 20: 47,735,307–47,736,306, 1,000 bases151015205′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.6 kb of the gene's 475.4 kb; 2,748 of those bases code for the protein.

How a genome test reads SPIDR

3

positions in SPIDR where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 475.4 kb of SPIDR, introns included, not only the 3.6 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). SPIDR gene: scaffold protein involved in DNA repair. Retrieved 17 October 2026, from https://dantelabs.com/genes/spidr

Vancouver

Dante Labs. SPIDR gene: scaffold protein involved in DNA repair [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/spidr

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