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Gene

SPAG8

sperm associated antigen 8

Summary

Cytogenetic location
9p13.3
Coordinates
Chromosome 9: 35,809,795–35,812,262 (GRCh38)
Exons
7 exons across 2.5 kb
Protein
485 amino acids
Also known as
hSMP-1, HSD-1, BS-84, SPAG3, CT142
MANE Select transcript
ENST00000396638.7NM_001039592.2
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads SPAG8 yet. The test sequences your whole genome, so your data includes it all the same.

How SPAG8 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
Chromosome 9, with a bracket where SPAG8 sits. SPAG8 and 31 genes near it on chromosome 9, from 35,311,029 to 36,311,028.Chromosome 99p13.3p24.3p24.2p24.1p23p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q13q21.11q21.12q21.13q21.2q21.31q21.32q21.33q22.1q22.2q22.31q22.32q22.33q31.1q31.2q31.3q32q33.1q33.2q33.3q34.11q34.12q34.13q34.2q34.335.4 Mb35.6 Mb35.8 Mb36 Mb36.2 MbUNC13B: 35,161,829–35,405,339, forward strandUNC13BRUSC2: 35,489,670–35,562,266, forward strandRUSC2CIMIP2B: 35,561,831–35,563,914, reverse strandCIMIP2BTESK1: 35,605,235–35,610,328, forward strandTESK1CD72: 35,609,965–35,646,810, reverse strandCD72SIT1: 35,649,288–35,650,970, reverse strandRMRP: 35,657,750–35,658,019, reverse strandCCDC107: 35,658,277–35,661,524, forward strandARHGEF39: 35,658,874–35,675,866, reverse strandARHGEF39CA9: 35,673,898–35,681,159, forward strandCA9TPM2: 35,681,992–35,691,116, reverse strandTPM2TLN1: 35,696,925–35,732,212, reverse strandCREB3: 35,732,296–35,738,887, forward strandCREB3GBA2: 35,734,577–35,749,986, reverse strandGBA2RGP1: 35,748,613–35,759,600, forward strandRGP1MSMP: 35,752,990–35,756,613, reverse strandMSMPNPR2: 35,791,003–35,809,732, forward strandNPR2SPAG8: 35,809,795–35,812,262, reverse strandSPAG8HINT2: 35,812,960–35,815,354, reverse strandHINT2: 35,812,960–35,828,732, reverse strandTMEM8B: 35,814,451–35,865,518, forward strandFAM221B: 35,816,391–35,828,747, reverse strandOR13J1: 35,869,463–35,870,401, reverse strandOR13J1HRCT1: 35,906,202–35,907,136, forward strandHRCT1SPAAR: 35,909,488–35,937,153, forward strandSPAAROR2S2: 35,957,108–35,958,154, reverse strandOR2S2OR13C7: 36,002,909–36,003,867, reverse strandOR13C7RECK: 36,036,896–36,124,457, forward strandRECKGLIPR2: 36,136,417–36,163,913, forward strandGLIPR2CCIN: 36,165,751–36,172,384, forward strandCCINCLTA: 36,190,856–36,304,781, forward strandCLTAGNE: 36,214,441–36,277,042, reverse strandGNEDiagram of SPAG8: 7 exons on the reverse strand of chromosome 9Exon 7: 35,809,795–35,810,132, 338 basesExon 6: 35,810,247–35,810,309, 63 basesExon 5: 35,810,439–35,810,553, 115 basesExon 4: 35,810,637–35,810,682, 46 basesExon 3: 35,810,883–35,811,057, 175 basesExon 2: 35,811,182–35,812,001, 820 basesExon 1: 35,812,104–35,812,262, 159 bases76543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.7 kb of the gene's 2.5 kb; 1,458 of those bases code for the protein.

How a genome test reads SPAG8

1

position in SPAG8 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 2.5 kb of SPAG8, introns included, not only the 1.7 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). SPAG8 gene: sperm associated antigen 8. Retrieved 17 October 2026, from https://dantelabs.com/genes/spag8

Vancouver

Dante Labs. SPAG8 gene: sperm associated antigen 8 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/spag8

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