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Gene

CREB3

cAMP responsive element binding protein 3

Summary

Cytogenetic location
9p13.3
Coordinates
Chromosome 9: 35,732,666–35,736,999 (GRCh38)
Exons
9 exons across 4.3 kb
Protein
371 amino acids
Also known as
LZIP, Luman, sLZIP
MANE Select transcript
ENST00000353704.3NM_006368.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads CREB3 yet. The test sequences your whole genome, so your data includes it all the same.

How CREB3 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
Chromosome 9, with a bracket where CREB3 sits. CREB3 and 31 genes near it on chromosome 9, from 35,234,833 to 36,234,832.Chromosome 99p13.3p24.3p24.2p24.1p23p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q13q21.11q21.12q21.13q21.2q21.31q21.32q21.33q22.1q22.2q22.31q22.32q22.33q31.1q31.2q31.3q32q33.1q33.2q33.3q34.11q34.12q34.13q34.2q34.335.4 Mb35.6 Mb35.8 Mb36 Mb36.2 MbUNC13B: 35,161,829–35,405,339, forward strandUNC13BRUSC2: 35,489,670–35,562,266, forward strandRUSC2CIMIP2B: 35,561,831–35,563,914, reverse strandCIMIP2BTESK1: 35,605,235–35,610,328, forward strandTESK1CD72: 35,609,965–35,646,810, reverse strandCD72SIT1: 35,649,288–35,650,970, reverse strandRMRP: 35,657,750–35,658,019, reverse strandRMRPCCDC107: 35,658,277–35,661,524, forward strandARHGEF39: 35,658,874–35,675,866, reverse strandARHGEF39CA9: 35,673,898–35,681,159, forward strandCA9TPM2: 35,681,992–35,691,116, reverse strandTPM2TLN1: 35,696,925–35,732,212, reverse strandCREB3: 35,732,666–35,736,999, forward strandCREB3GBA2: 35,734,577–35,749,986, reverse strandGBA2RGP1: 35,748,613–35,759,600, forward strandRGP1MSMP: 35,752,990–35,756,613, reverse strandMSMPNPR2: 35,791,003–35,809,732, forward strandNPR2SPAG8: 35,808,045–35,812,272, reverse strandSPAG8HINT2: 35,812,960–35,815,354, reverse strandHINT2: 35,812,960–35,828,732, reverse strandTMEM8B: 35,814,451–35,865,518, forward strandFAM221B: 35,816,391–35,828,747, reverse strandOR13J1: 35,869,463–35,870,401, reverse strandOR13J1HRCT1: 35,906,202–35,907,136, forward strandHRCT1SPAAR: 35,909,488–35,937,153, forward strandSPAAROR2S2: 35,957,108–35,958,154, reverse strandOR2S2OR13C7: 36,002,909–36,003,867, reverse strandOR13C7RECK: 36,036,896–36,124,457, forward strandRECKGLIPR2: 36,136,417–36,163,913, forward strandGLIPR2CCIN: 36,165,751–36,172,384, forward strandCCINCLTA: 36,190,856–36,304,781, forward strandCLTAGNE: 36,214,441–36,277,042, reverse strandGNEDiagram of CREB3: 9 exons on the forward strand of chromosome 9Exon 1: 35,732,666–35,732,901, 236 basesExon 2: 35,732,996–35,733,143, 148 basesExon 3: 35,733,215–35,733,282, 68 basesExon 4: 35,733,396–35,733,485, 90 basesExon 5: 35,735,109–35,735,215, 107 basesExon 6: 35,735,306–35,735,374, 69 basesExon 7: 35,736,048–35,736,132, 85 basesExon 8: 35,736,227–35,736,311, 85 basesExon 9: 35,736,392–35,736,999, 608 bases1234567895′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.5 kb of the gene's 4.3 kb; 1,116 of those bases code for the protein.

How a genome test reads CREB3

1

position in CREB3 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 4.3 kb of CREB3, introns included, not only the 1.5 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). CREB3 gene: cAMP responsive element binding protein 3. Retrieved 17 October 2026, from https://dantelabs.com/genes/creb3

Vancouver

Dante Labs. CREB3 gene: cAMP responsive element binding protein 3 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/creb3

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