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Gene

PPARGC1A

PPARG coactivator 1 alpha

Summary

Cytogenetic location
4p15.2
Coordinates
Chromosome 4: 23,792,021–23,890,047 (GRCh38)
Exons
13 exons across 98 kb
Protein
798 amino acids
Also known as
PGC1, PGC1A, PGC-1alpha, PPARAGCIα
Previous symbols
PPARGC1
MANE Select transcript
ENST00000264867.7NM_013261.5
Locus type
Protein-coding
  • Very high
  • Confident
  • Low
  • Very low

Trait report that reads PPARGC1A

How PPARGC1A is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 4, with a bracket where PPARGC1A sits. PPARGC1A and 0 genes near it on chromosome 4, from 23,341,034 to 24,341,033.Chromosome 44p15.2p16.3p16.2p16.1p15.33p15.32p15.31p15.2p15.1p14p13p12p11q11q12q13.1q13.2q13.3q21.1q21.21q21.22q21.23q21.3q22.1q22.2q22.3q23q24q25q26q27q28.1q28.2q28.3q31.1q31.21q31.22q31.23q31.3q32.1q32.2q32.3q33q34.1q34.2q34.3q35.1q35.223.4 Mb23.6 Mb23.8 Mb24 Mb24.2 MbPPARGC1A: 23,792,021–23,890,047, reverse strandPPARGC1ADiagram of PPARGC1A: 13 exons on the reverse strand of chromosome 4Exon 13: 23,792,021–23,795,925, 3,905 basesExon 12: 23,801,730–23,801,881, 152 basesExon 11: 23,802,224–23,802,345, 122 basesExon 10: 23,812,747–23,812,867, 121 basesExon 9: 23,813,021–23,813,125, 105 basesExon 8: 23,813,690–23,814,605, 916 basesExon 7: 23,824,280–23,824,353, 74 basesExon 6: 23,824,463–23,824,508, 46 basesExon 5: 23,828,400–23,828,604, 205 basesExon 4: 23,829,463–23,829,585, 123 basesExon 3: 23,831,557–23,831,751, 195 basesExon 2: 23,884,752–23,884,931, 180 basesExon 1: 23,889,904–23,890,047, 144 bases1310515′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 6.3 kb of the gene's 98 kb; 2,397 of those bases code for the protein.

Sequencing PPARGC1A

3Easy

How hard PPARGC1A is to sequence with short reads, out of 100

Almost all of PPARGC1A's exons sit where short reads map cleanly.

What adds to it: the share of PPARGC1A's exons in each kind of hard region

  • Mappability0%
  • Homology0%
  • Shared with chrY0%
  • Reference coverage0%
  • Repeats6.2%
  • GC content7.5%

A Dante Labs score from our own research, built on NIST's Genome in a Bottle maps of hard-to-sequence regions.How it's scored

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Genome in a Bottle genome stratifications, from NIST: the sequencing difficulty score.

Cite this page

APA

Dante Labs. (n.d.). PPARGC1A gene: PPARG coactivator 1 alpha. Retrieved 19 October 2026, from https://dantelabs.com/genes/ppargc1a

Vancouver

Dante Labs. PPARGC1A gene: PPARG coactivator 1 alpha [Internet]. [cited 19 October 2026]. Available from: https://dantelabs.com/genes/ppargc1a

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