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Gene

PDE1C

phosphodiesterase 1C

Summary

Cytogenetic location
7p14.3
Coordinates
Chromosome 7: 31,751,179–32,070,407 (GRCh38)
Exons
18 exons across 319.2 kb
Protein
709 amino acids
Also known as
Hcam3
MANE Select transcript
ENST00000396191.6NM_001191057.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads PDE1C yet. The test sequences your whole genome, so your data includes it all the same.

How PDE1C is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 7, with a bracket where PDE1C sits. PDE1C and 2 genes near it on chromosome 7, from 31,410,793 to 32,410,792.Chromosome 77p14.3p22.3p22.2p22.1p21.3p21.2p21.1p15.3p15.2p15.1p14.3p14.2p14.1p13p12.3p12.2p12.1p11.2p11.1q11.1q11.21q11.22q11.23q21.11q21.12q21.13q21.2q21.3q22.1q22.2q22.3q31.1q31.2q31.31q31.32q31.33q32.1q32.2q32.3q33q34q35q36.1q36.2q36.331.6 Mb31.8 Mb32 Mb32.2 Mb32.4 MbITPRID1: 31,514,090–31,656,504, forward strandITPRID1PPP1R17: 31,687,178–31,709,288, forward strandPPP1R17PDE1C: 31,751,179–32,070,407, reverse strandPDE1CDiagram of PDE1C: 18 exons on the reverse strand of chromosome 7Exon 18: 1 known disease-causing siteExon 17: 1 known disease-causing siteExon 11: 1 known disease-causing siteExon 18: 31,751,179–31,753,553, 2,375 basesExon 17: 31,775,664–31,775,732, 69 basesExon 16: 31,809,031–31,809,108, 78 basesExon 15: 31,815,924–31,816,154, 231 basesExon 14: 31,823,073–31,823,248, 176 basesExon 13: 31,824,867–31,824,987, 121 basesExon 12: 31,828,292–31,828,373, 82 basesExon 11: 31,837,180–31,837,300, 121 basesExon 10: 31,837,870–31,837,971, 102 basesExon 9: 31,847,968–31,848,096, 129 basesExon 8: 31,850,641–31,850,741, 101 basesExon 7: 31,864,942–31,865,082, 141 basesExon 6: 31,873,292–31,873,408, 117 basesExon 5: 31,877,970–31,878,036, 67 basesExon 4: 31,878,996–31,879,178, 183 basesExon 3: 31,880,747–31,880,860, 114 basesExon 2: 32,051,554–32,051,580, 27 basesExon 1: 32,070,293–32,070,407, 115 bases181510515′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 4.3 kb of the gene's 319.2 kb; 2,130 of those bases code for the protein.

How a genome test reads PDE1C

4

positions in PDE1C where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 319.2 kb of PDE1C, introns included, not only the 4.3 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). PDE1C gene: phosphodiesterase 1C. Retrieved 16 October 2026, from https://dantelabs.com/genes/pde1c

Vancouver

Dante Labs. PDE1C gene: phosphodiesterase 1C [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/pde1c

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