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Traits

Traits linked to NLGN3

neuroligin 3

The Human Phenotype Ontology links 13 traits to NLGN3, by body system: features seen in people with one of the gene's rare conditions.

Abnormality of the nervous system

TraitHow often it is seen
AutismOften (30–79%)
Delayed speech and language developmentOften (30–79%)
EEG abnormalityOften (30–79%)
EpilepsyOften (30–79%)
Impaired use of nonverbal behaviorsNot recorded
Inflexible adherence to routinesNot recorded
Intellectual disabilityNot recorded
Lack of peer relationshipsNot recorded
Lack of spontaneous playNot recorded
Reduced ability to form peer relationshipsNot recorded
Repetitive movementsNot recorded
Restrictive behaviorNot recorded

Abnormality of the endocrine system

TraitHow often it is seen
Increased serum serotoninOften (30–79%)

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Where this comes from

  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to NLGN3 and how often each is seen. Find out more at hpo.jax.org.

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