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Gene

NHERF2

NHERF family PDZ scaffold protein 2

Summary

Cytogenetic location
16p13.3
Coordinates
Chromosome 16: 2,026,902–2,039,026 (GRCh38)
Exons
7 exons across 12.1 kb
Protein
337 amino acids
Also known as
SIP-1, TKA-1, NHERF-2, E3KARP, OCTS2
Previous symbols
SLC9A3R2
MANE Select transcript
ENST00000424542.7NM_001130012.3
Locus type
gene with protein product

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads NHERF2 yet. The test sequences your whole genome, so your data includes it all the same.

How NHERF2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 16, with a bracket where NHERF2 sits. NHERF2 and 50 genes near it on chromosome 16, from 1,532,964 to 2,532,963.Chromosome 1616p13.3p13.3p13.2p13.13p13.12p13.11p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12.1q12.2q13q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.31.6 Mb1.8 Mb2 Mb2.2 Mb2.4 MbIFT140: 1,510,427–1,612,082, reverse strandIFT140TMEM204: 1,528,674–1,555,580, forward strandTMEM204CRAMP1: 1,612,337–1,677,908, forward strandCRAMP1: 1,632,259–1,686,715, forward strandJPT2: 1,678,256–1,702,859, forward strandJPT2MAPK8IP3: 1,706,166–1,770,374, forward strandNME3: 1,770,317–1,771,746, reverse strandMRPS34: 1,771,889–1,773,487, reverse strandEME2: 1,772,283–1,781,708, forward strandSPSB3: 1,776,710–1,793,700, reverse strandNUBP2: 1,782,932–1,789,189, forward strandNUBP2IGFALS: 1,790,227–1,794,971, reverse strandIGFALSHAGH: 1,795,620–1,827,187, reverse strandHAGHFAHD1: 1,826,967–1,842,053, forward strandFAHD1MEIOB: 1,833,986–1,884,294, reverse strandMEIOBHS3ST6: 1,911,475–1,918,415, reverse strandHS3ST6MSRB1: 1,935,685–1,943,270, reverse strandMSRB1RPL3L: 1,943,791–1,957,606, reverse strandNDUFB10: 1,959,500–1,962,105, forward strandRPS2: 1,961,987–1,965,510, reverse strandRNF151: 1,966,823–1,968,975, forward strandTBL3: 1,971,972–1,983,056, forward strandNOXO1: 1,978,912–1,984,636, reverse strandGFER: 1,983,699–1,987,749, forward strandGFERSYNGR3: 1,989,637–1,994,275, forward strandZNF598: 1,997,654–2,009,821, reverse strandZNF598NPW: 2,009,926–2,020,755, forward strandNPWNHERF2: 2,026,902–2,039,026, forward strandNHERF2NTHL1: 2,039,814–2,047,866, reverse strandNTHL1TSC2: 2,047,345–2,089,491, forward strandTSC2PKD1: 2,088,708–2,135,898, reverse strandPKD1RAB26: 2,140,803–2,154,165, forward strandRAB26TRAF7: 2,155,692–2,178,129, forward strandTRAF7CASKIN1: 2,177,180–2,196,788, reverse strandCASKIN1MLST8: 2,204,248–2,209,453, forward strandMLST8BRICD5: 2,209,252–2,210,905, reverse strandBRICD5PGP: 2,211,593–2,214,846, reverse strandPGPE4F1: 2,223,440–2,235,743, forward strandDNASE1L2: 2,235,816–2,238,711, forward strandECI1: 2,239,376–2,252,300, reverse strandRNPS1: 2,253,116–2,268,413, reverse strandRNPS1ABCA3: 2,275,878–2,340,788, reverse strandABCA3CCNF: 2,429,394–2,458,913, forward strandCCNFTEDC2: 2,460,085–2,464,963, forward strandTEDC2NTN3: 2,471,286–2,474,145, forward strandNTN3TBC1D24: 2,475,051–2,509,671, forward strandTBC1D24: 2,496,032–2,520,218, forward strandATP6V0C: 2,513,713–2,520,218, forward strand: 2,513,965–2,527,955, forward strandAMDHD2: 2,520,340–2,531,422, forward strandCEMP1: 2,530,035–2,531,417, reverse strandDiagram of NHERF2: 7 exons on the forward strand of chromosome 16Exon 1: 2,026,902–2,027,218, 317 basesExon 2: 2,029,582–2,029,782, 201 basesExon 3: 2,036,324–2,036,503, 180 basesExon 4: 2,036,728–2,036,881, 154 basesExon 5: 2,036,955–2,036,998, 44 basesExon 6: 2,037,538–2,037,600, 63 basesExon 7: 2,037,826–2,039,026, 1,201 bases124675′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.2 kb of the gene's 12.1 kb; 1,014 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). NHERF2 gene: NHERF family PDZ scaffold protein 2. Retrieved 16 October 2026, from https://dantelabs.com/genes/nherf2

Vancouver

Dante Labs. NHERF2 gene: NHERF family PDZ scaffold protein 2 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/nherf2

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