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Gene

NEMF

nuclear export mediator factor

Summary

Cytogenetic location
14q21.3
Coordinates
Chromosome 14: 49,782,083–49,852,788 (GRCh38)
Exons
33 exons across 70.7 kb
Protein
1,076 amino acids
Also known as
NY-CO-1, FLJ10051, RQC2
Previous symbols
SDCCAG1
MANE Select transcript
ENST00000298310.10NM_004713.6
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads NEMF yet. The test sequences your whole genome, so your data includes it all the same.

How NEMF is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 14, with a bracket where NEMF sits. NEMF and 13 genes near it on chromosome 14, from 49,317,436 to 50,317,435.Chromosome 1414q21.3p13p12p11.2p11.1q11.1q11.2q12q13.1q13.2q13.3q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q31.1q31.2q31.3q32.11q32.12q32.13q32.2q32.31q32.32q32.3349.4 Mb49.6 Mb49.8 Mb50 Mb50.2 MbRPS29: 49,500,452–49,599,164, reverse strandLRR1: 49,598,480–49,614,673, forward strandLRR1RPL36AL: 49,600,815–49,620,649, reverse strandRPL36ALMGAT2: 49,620,799–49,633,312, forward strandMGAT2DNAAF2: 49,623,701–49,635,284, reverse strandDNAAF2POLE2: 49,643,555–49,688,422, reverse strandPOLE2KLHDC1: 49,693,100–49,753,636, forward strandKLHDC1KLHDC2: 49,767,540–49,828,902, forward strandKLHDC2NEMF: 49,782,083–49,852,788, reverse strandNEMFARF6: 49,892,608–49,897,202, forward strandARF6VCPKMT: 50,108,631–50,116,600, reverse strandVCPKMTSOS2: 50,116,801–50,231,930, reverse strandSOS2L2HGDH: 50,237,563–50,312,243, reverse strandL2HGDHDMAC2L: 50,311,516–50,356,756, forward strandDMAC2LDiagram of NEMF: 33 exons on the reverse strand of chromosome 14Exon 30: 1 known disease-causing siteExon 23: 1 known disease-causing siteExon 22: 1 known disease-causing siteExon 14: 2 known disease-causing sitesExon 13: 1 known disease-causing siteExon 6: 1 known disease-causing siteExon 33: 49,782,083–49,784,713, 2,631 basesExon 32: 49,784,925–49,785,004, 80 basesExon 31: 49,785,092–49,785,135, 44 basesExon 30: 49,785,220–49,785,320, 101 basesExon 29: 49,786,718–49,786,750, 33 basesExon 28: 49,789,146–49,789,343, 198 basesExon 27: 49,789,496–49,789,573, 78 basesExon 26: 49,795,791–49,795,944, 154 basesExon 25: 49,799,475–49,799,524, 50 basesExon 24: 49,799,636–49,799,678, 43 basesExon 23: 49,800,420–49,800,696, 277 basesExon 22: 49,802,453–49,802,573, 121 basesExon 21: 49,802,669–49,802,727, 59 basesExon 20: 49,803,237–49,803,294, 58 basesExon 19: 49,806,021–49,806,133, 113 basesExon 18: 49,813,988–49,814,050, 63 basesExon 17: 49,814,754–49,814,857, 104 basesExon 16: 49,825,867–49,825,955, 89 basesExon 15: 49,828,291–49,828,354, 64 basesExon 14: 49,828,616–49,828,807, 192 basesExon 13: 49,829,054–49,829,262, 209 basesExon 12: 49,829,349–49,829,426, 78 basesExon 11: 49,831,299–49,831,361, 63 basesExon 10: 49,832,051–49,832,126, 76 basesExon 9: 49,832,207–49,832,277, 71 basesExon 8: 49,833,423–49,833,496, 74 basesExon 7: 49,834,363–49,834,449, 87 basesExon 6: 49,838,139–49,838,206, 68 basesExon 5: 49,840,718–49,840,866, 149 basesExon 4: 49,846,140–49,846,265, 126 basesExon 3: 49,851,563–49,851,665, 103 basesExon 2: 49,851,807–49,851,875, 69 basesExon 1: 49,852,695–49,852,788, 94 bases333025201510515′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 5.8 kb of the gene's 70.7 kb; 3,231 of those bases code for the protein.

How a genome test reads NEMF

8

positions in NEMF where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 70.7 kb of NEMF, introns included, not only the 5.8 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). NEMF gene: nuclear export mediator factor. Retrieved 17 October 2026, from https://dantelabs.com/genes/nemf

Vancouver

Dante Labs. NEMF gene: nuclear export mediator factor [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/nemf

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