Gene
LYRM4
LYR motif containing 4
- HGNC 21365↗(opens in a new tab)
- Ensembl gene ENSG00000214113↗(opens in a new tab)
- NCBI Gene 57128↗(opens in a new tab)
Summary
- Cytogenetic location
- 6p25.1
- Coordinates
- Chromosome 6: 5,108,419–5,260,950 (GRCh38)
- Exons
- 3 exons across 152.5 kb
- Protein
- 91 amino acids
- Also known as
- CGI-203, ISD11
- Previous symbols
- C6orf149
- MANE Select transcript
- ENST00000330636.9NM_020408.6
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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How LYRM4 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 1.5 kb of the gene's 152.5 kb; 276 of those bases code for the protein.
Traits linked to LYRM4
The Human Phenotype Ontology lists these as features of the rare conditions LYRM4 can cause. Each trait's page lists the other genes linked to it.
Laboratory abnormality
- High urine lactic acid levels
- Increased lactate in body
- Metabolic acidosis
- Elevated circulating alanine aminotransferase concentration
- Elevated circulating aspartate aminotransferase concentration
- Elevated gamma-glutamyltransferase level
- High levels of ketone bodies
- Increased CSF lactate
Show 2 more traits
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
Cite this page
Dante Labs. (n.d.). LYRM4 gene: LYR motif containing 4. Retrieved 16 October 2026, from https://dantelabs.com/genes/lyrm4
Dante Labs. LYRM4 gene: LYR motif containing 4 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/lyrm4
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