Traits

Traits linked to ITGB2

integrin subunit beta 2

The Human Phenotype Ontology links 17 traits to ITGB2, by body system: features seen in people with one of the gene's rare conditions.

Abnormality of the immune system

Trait	How often it is seen
Recurrent bacterial infections	Always
Recurrent infections	Always
Recurrent mucocutaneous candidiasis	Always
Bone infection	Sometimes (5–29%)
Recurrent gram-negative bacterial infections	Not recorded
Recurrent staphylococcal infections	Not recorded

Abnormality of blood and blood-forming tissues

Trait	How often it is seen
Elevated white blood count	Always
Hyperfibrinogenemia	Always

Abnormality of head or neck

Trait	How often it is seen
Inflamed gums	Always
Gum disease	Not recorded

Abnormality of prenatal development or birth

Trait	How often it is seen
Delayed umbilical cord separation	Always
Neonatal omphalitis	Sometimes (5–29%)

Abnormality of the digestive system

Trait	How often it is seen
Chronic diarrhea	Always
Rectal abscess	Not recorded

Abnormality of the integument

Trait	How often it is seen
Open skin sore	Sometimes (5–29%)
Poor wound healing	Not recorded

Laboratory abnormality

Trait	How often it is seen
Elevated circulating C-reactive protein concentration	Always

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the traits linked to ITGB2 and how often each is seen. Find out more at hpo.jax.org.

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test