Traits

Traits linked to IL17RC

interleukin 17 receptor C

The Human Phenotype Ontology links 35 traits to IL17RC, by body system: features seen in people with one of the gene's rare conditions.

Abnormality of the integument

Trait	How often it is seen
Abnormal fingernails	Very often (80–99%)
Abnormality of the nail	Very often (80–99%)
Abnormality of the skin	Very often (80–99%)
Abnormality of the toenail	Very often (80–99%)
Broad nail	Very often (80–99%)
Hyperkeratosis	Very often (80–99%)
Open skin sore	Very often (80–99%)
Papule	Often (30–79%)
Itching	Sometimes (5–29%)

Abnormality of the immune system

Trait	How often it is seen
Recurrent mucocutaneous candidiasis	Always
Abnormality of the immune system	Very often (80–99%)
Recurrent infections	Very often (80–99%)
Skin rash	Very often (80–99%)
Unusual fungal nail infection	Often (30–79%)
Recurrent respiratory infections	Sometimes (5–29%)

Abnormality of head or neck

Trait	How often it is seen
Abnormal lip	Very often (80–99%)
Abnormality of the mouth	Very often (80–99%)
Inflammation of the lips	Very often (80–99%)
Recurrent canker sores	Often (30–79%)
Abnormal tooth enamel	Sometimes (5–29%)

Abnormality of the digestive system

Trait	How often it is seen
Candida esophagitis	Often (30–79%)
Feeding difficulties in infancy	Sometimes (5–29%)
Liver inflammation	Sometimes (5–29%)

Abnormality of the genitourinary system

Trait	How often it is seen
Abnormal vagina morphology	Often (30–79%)
Dyspareunia	Often (30–79%)
Frequent urinary tract infections	Sometimes (5–29%)

Abnormality of the cardiovascular system

Trait	How often it is seen
Redness of skin or mucous membrane	Very often (80–99%)
Abnormal endocardium morphology	Sometimes (5–29%)

Abnormality of the eye

Trait	How often it is seen
Abnormality of the eye	Sometimes (5–29%)
Abnormality of vision	Sometimes (5–29%)

Abnormality of the respiratory system

Trait	How often it is seen
Cough	Sometimes (5–29%)
Coughing up blood	Sometimes (5–29%)

Laboratory abnormality

Trait	How often it is seen
Abnormality of temperature regulation	Sometimes (5–29%)
Blood in urine	Sometimes (5–29%)

Abnormality of the nervous system

Trait	How often it is seen
Epilepsy	Sometimes (5–29%)

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the traits linked to IL17RC and how often each is seen. Find out more at hpo.jax.org.

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