Gene
FLRT1
fibronectin leucine rich transmembrane protein 1
- HGNC 3760↗(opens in a new tab)
- Ensembl gene ENSG00000126500↗(opens in a new tab)
- NCBI Gene 23769↗(opens in a new tab)
Summary
- Cytogenetic location
- 11q13.1
- Coordinates
- Chromosome 11: 64,035,931–64,119,171 (GRCh38)
- Exons
- 3 exons across 83.2 kb
- Protein
- 674 amino acids
- Also known as
- MGC21624, SPG68
- MANE Select transcript
- ENST00000682287.1NM_013280.5
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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How FLRT1 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 4.2 kb of the gene's 83.2 kb; 2,025 of those bases code for the protein.
Traits linked to FLRT1
The Human Phenotype Ontology lists these as features of the rare conditions FLRT1 can cause. Each trait's page lists the other genes linked to it.
Abnormality of the nervous system
- Abnormal gait
- Decreased number of peripheral myelinated nerve fibers
- Delayed motor skills
- Difficulty articulating speech
- Exaggerated startle response
- Impaired vibration sensation in the lower limbs
- Peripheral axonal neuropathy
- Proximal hyperreflexia
Show 1 more trait
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
Cite this page
Dante Labs. (n.d.). FLRT1 gene: fibronectin leucine rich transmembrane protein 1. Retrieved 16 October 2026, from https://dantelabs.com/genes/flrt1
Dante Labs. FLRT1 gene: fibronectin leucine rich transmembrane protein 1 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/flrt1
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