Traits

Traits linked to DOCK3

dedicator of cytokinesis 3

The Human Phenotype Ontology links 20 traits to DOCK3, by body system: features seen in people with one of the gene's rare conditions.

Abnormality of head or neck

Trait	How often it is seen
Bad bite	Often (30–79%)
Big lower jaw	Often (30–79%)
Downward slanting of the opening between the eyelids	Often (30–79%)
High palate	Often (30–79%)
Long face	Often (30–79%)
Pointed chin	Often (30–79%)
Relatively large head	Often (30–79%)
Eye folds	Not recorded
Nasal tip, upturned	Not recorded

Abnormality of the nervous system

Trait	How often it is seen
Delayed ability to walk	Always
Global developmental delay	Always
Inability to coordinate movements when walking	Always
Absent speech development	Often (30–79%)
Diminished deep tendon reflex	Often (30–79%)
Unsteady walk	Often (30–79%)
Decreased reflex response	Not recorded

Abnormality of limbs

Trait	How often it is seen
Long fingers	Often (30–79%)
Tapered finger	Not recorded

Abnormality of the musculoskeletal system

Trait	How often it is seen
Low muscle tone	Always

Growth abnormality

Trait	How often it is seen
Mild short stature	Not recorded

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the traits linked to DOCK3 and how often each is seen. Find out more at hpo.jax.org.

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test