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Gene

DDIT3

DNA damage inducible transcript 3

Summary

Cytogenetic location
12q13.3
Coordinates
Chromosome 12: 57,516,593–57,520,514 (GRCh38)
Exons
4 exons across 3.9 kb
Protein
169 amino acids
Also known as
CHOP10, GADD153, CHOP
MANE Select transcript
ENST00000346473.8NM_004083.6
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads DDIT3 yet. The test sequences your whole genome, so your data includes it all the same.

How DDIT3 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
Chromosome 12, with a bracket where DDIT3 sits. DDIT3 and 39 genes near it on chromosome 12, from 57,018,554 to 58,018,553.Chromosome 1212q13.3p13.33p13.32p13.31p13.2p13.1p12.3p12.2p12.1p11.23p11.22p11.21p11.1q11q12q13.11q13.12q13.13q13.2q13.3q14.1q14.2q14.3q15q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.11q24.12q24.13q24.21q24.22q24.23q24.31q24.32q24.3357.2 Mb57.4 Mb57.6 Mb57.8 Mb58 MbTAC3: 57,010,000–57,028,883, reverse strandTAC3MYO1A: 57,025,262–57,051,198, reverse strandMYO1ANEMP1: 57,055,641–57,088,063, reverse strandNEMP1NAB2: 57,088,883–57,095,476, forward strandNAB2STAT6: 57,095,403–57,132,139, reverse strandSTAT6LRP1: 57,128,476–57,213,394, forward strandLRP1NXPH4: 57,216,780–57,226,449, forward strandSHMT2: 57,226,554–57,234,935, forward strandCOXFA4L2: 57,234,541–57,242,750, reverse strandCOXFA4L2STAC3: 57,243,453–57,251,195, reverse strandSTAC3: 57,249,609–57,296,484, reverse strandR3HDM2: 57,253,762–57,431,051, reverse strandR3HDM2INHBC: 57,434,700–57,452,067, forward strandINHBCINHBE: 57,452,323–57,459,280, forward strandINHBEGLI1: 57,459,783–57,472,268, forward strandGLI1ARHGAP9: 57,472,260–57,488,831, reverse strandMARS1: 57,475,445–57,517,702, forward strandDDIT3: 57,516,593–57,520,514, reverse strandDDIT3: 57,517,712–57,520,480, reverse strandMBD6: 57,520,710–57,530,614, forward strandMBD6DCTN2: 57,529,567–57,547,256, reverse strandDCTN2KIF5A: 57,546,026–57,586,633, forward strandKIF5APIP4K2C: 57,591,161–57,603,418, forward strandPIP4K2CDTX3: 57,604,484–57,609,804, forward strandDTX3ARHGEF25: 57,610,111–57,617,245, forward strandARHGEF25: 57,615,280–57,626,125, forward strandB4GALNT1: 57,623,409–57,633,242, reverse strandOS9: 57,693,841–57,728,342, forward strandOS9AGAP2: 57,723,761–57,742,209, reverse strandAGAP2TSPAN31: 57,738,013–57,751,383, forward strandTSPAN31CDK4: 57,746,043–57,756,013, reverse strandCDK4MARCHF9: 57,754,940–57,760,411, forward strandCYP27B1: 57,762,334–57,768,986, reverse strandMETTL1: 57,768,471–57,772,131, reverse strandEEF1AKMT3: 57,771,492–57,782,544, forward strand: 57,772,660–57,797,554, forward strandTSFM: 57,782,731–57,828,655, forward strandTSFMAVIL: 57,797,376–57,818,734, reverse strandAVILCTDSP2: 57,819,925–57,846,976, reverse strandCTDSP2ATP23: 57,906,039–57,959,148, forward strandATP23Diagram of DDIT3: 4 exons on the reverse strand of chromosome 12Exon 4: 57,516,593–57,517,180, 588 basesExon 3: 57,517,269–57,517,438, 170 basesExon 2: 57,517,706–57,517,753, 48 basesExon 1: 57,520,418–57,520,514, 97 bases43215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 0.9 kb of the gene's 3.9 kb; 510 of those bases code for the protein.

Traits linked to DDIT3

The Human Phenotype Ontology lists these as features of the rare conditions DDIT3 can cause. Each trait's page lists the other genes linked to it.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.

Cite this page

APA

Dante Labs. (n.d.). DDIT3 gene: DNA damage inducible transcript 3. Retrieved 17 October 2026, from https://dantelabs.com/genes/ddit3

Vancouver

Dante Labs. DDIT3 gene: DNA damage inducible transcript 3 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/ddit3

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