Traits

Traits linked to BIRC3

baculoviral IAP repeat containing 3

The Human Phenotype Ontology links 17 traits to BIRC3, by body system: features seen in people with one of the gene's rare conditions.

Abnormality of the digestive system

Trait	How often it is seen
Nausea and vomiting	Very often (80–99%)
Constipation	Often (30–79%)
Abdominal pain	Sometimes (5–29%)

Abnormality of blood and blood-forming tissues

Trait	How often it is seen
B-cell lymphoma	Very often (80–99%)
Low number of red blood cells or hemoglobin	Very often (80–99%)

Abnormality of the cardiovascular system

Trait	How often it is seen
Swollen lymph nodes	Sometimes (5–29%)
Swollen lymph nodes in center of chest	Sometimes (5–29%)

Abnormality of the eye

Trait	How often it is seen
Posterior uveitis	Sometimes (5–29%)
Visual impairment	Sometimes (5–29%)

Abnormality of head or neck

Trait	How often it is seen
Abnormal nasolacrimal system morphology	Sometimes (5–29%)

Abnormality of the endocrine system

Trait	How often it is seen
Abnormality of the thyroid gland	Sometimes (5–29%)

Abnormality of the immune system

Trait	How often it is seen
Recurrent respiratory infections	Sometimes (5–29%)

Abnormality of the integument

Trait	How often it is seen
Excessive sweating	Very often (80–99%)

Abnormality of the respiratory system

Trait	How often it is seen
Lung infiltrates	Very often (80–99%)

Constitutional symptom

Trait	How often it is seen
Fatigue	Very often (80–99%)

Growth abnormality

Trait	How often it is seen
Weight loss	Very often (80–99%)

Laboratory abnormality

Trait	How often it is seen
Fever	Very often (80–99%)

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the traits linked to BIRC3 and how often each is seen. Find out more at hpo.jax.org.

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