Trait
Reduced antithrombin III activity
An abnormality of coagulation related to a decreased concentration of antithrombin-III.
Summary
- Also called
- Anti-thrombin III deficiency, Antithrombin III deficiency, Decreased antithrombin III
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Reduced antithrombin III activity, and the rest of your genome, with one test.
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Get my Genome Test16 genes linked to Reduced antithrombin III activity
Changes in these genes cause rare conditions in which Reduced antithrombin III activity is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| ALG12ALG12 alpha-1,6-mannosyltransferase | Always | In 1 condition |
| ALG8ALG8 alpha-1,3-glucosyltransferase | Always | In 2 conditions |
| ALG9ALG9 alpha-1,2-mannosyltransferase | Always | In 1 condition |
| SLC37A4solute carrier family 37 member 4 | Always | In 1 condition |
| SRD5A3steroid 5 alpha-reductase 3 | Always | In 2 conditions |
| SERPINC1serpin family C member 1 | Very often (80–99%) | In 2 conditions |
| AHCYadenosylhomocysteinase | Often (30–79%) | In 1 condition |
| B4GALT1beta-1,4-galactosyltransferase 1 | Often (30–79%) | In 1 condition |
| DPM1dolichyl-phosphate mannosyltransferase subunit 1, catalytic | Often (30–79%) | In 2 conditions |
| DPAGT1dolichyl-phosphate N-acetylglucosaminephosphotransferase 1 | Sometimes (5–29%) | In 2 conditions |
| DPM2dolichyl-phosphate mannosyltransferase subunit 2, regulatory | Sometimes (5–29%) | In 1 condition |
| PGM1phosphoglucomutase 1 | Sometimes (5–29%) | In 1 condition |
| PMM2phosphomannomutase 2 | Sometimes (5–29%) | In 2 conditions |
| ALG6ALG6 alpha-1,3-glucosyltransferase | Not recorded | In 1 condition |
| MGAT2alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | Not recorded | In 1 condition |
| MPImannose phosphate isomerase | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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