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Gene

ZBTB22

zinc finger and BTB domain containing 22

Summary

Cytogenetic location
6p21.32
Coordinates
Chromosome 6: 33,314,418–33,317,744 (GRCh38)
Exons
2 exons across 3.3 kb
Protein
634 amino acids
Also known as
BING1, ZNF297A, fruitless, fru, ZBTB22A
Previous symbols
ZNF297
MANE Select transcript
ENST00000431845.3NM_005453.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads ZBTB22 yet. The test sequences your whole genome, so your data includes it all the same.

How ZBTB22 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 6, with a bracket where ZBTB22 sits. ZBTB22 and 39 genes near it on chromosome 6, from 32,816,081 to 33,816,080.Chromosome 66p21.32p25.3p25.2p25.1p24.3p24.2p24.1p23p22.3p22.2p22.1p21.33p21.32p21.31p21.2p21.1p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12q13q14.1q14.2q14.3q15q16.1q16.2q16.3q21q22.1q22.2q22.31q22.32q22.33q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q26q2733 Mb33.2 Mb33.4 Mb33.6 Mb33.8 MbHLA-DOB: 32,812,763–32,820,466, reverse strand: 32,813,767–32,838,822, reverse strandTAP2: 32,821,833–32,838,802, reverse strandTAP2PSMB8: 32,840,717–32,844,679, reverse strandPSMB8PSMB9: 32,844,136–32,882,881, forward strandPSMB9TAP1: 32,845,204–32,854,026, reverse strandTAP1HLA-DMB: 32,929,338–32,941,490, reverse strandHLA-DMB: 32,937,364–32,953,122, reverse strandHLA-DMA: 32,948,613–32,969,094, reverse strandHLA-DMABRD2: 32,968,564–32,981,505, forward strandBRD2HLA-DOA: 33,004,178–33,009,617, reverse strandHLA-DOAHLA-DPA1: 33,064,569–33,080,781, reverse strandHLA-DPA1HLA-DPB1: 33,073,786–33,091,655, forward strandHLA-DPB1COL11A2: 33,162,681–33,192,802, reverse strandRXRB: 33,193,585–33,200,693, reverse strandRXRBSLC39A7: 33,200,305–33,204,439, forward strandSLC39A7HSD17B8: 33,204,631–33,206,831, forward strandHSD17B8RING1: 33,208,033–33,212,722, forward strandRING1VPS52: 33,250,272–33,272,047, reverse strandRPS18: 33,271,730–33,276,513, forward strandB3GALT4: 33,277,123–33,284,832, forward strandWDR46: 33,279,103–33,289,523, reverse strandPFDN6: 33,288,680–33,298,441, forward strandRGL2: 33,291,180–33,299,534, reverse strandTAPBP: 33,299,694–33,314,284, reverse strandTAPBPZBTB22: 33,314,418–33,317,744, reverse strandZBTB22DAXX: 33,318,558–33,323,259, reverse strandDAXX: 33,321,386–33,329,286, reverse strandSMIM40: 33,323,628–33,329,279, reverse strandKIFC1: 33,391,429–33,410,441, forward strandKIFC1PHF1: 33,410,360–33,416,453, forward strandPHF1CUTA: 33,416,442–33,418,381, reverse strandCUTASYNGAP1: 33,419,661–33,453,689, forward strandSYNGAP1ZBTB9: 33,453,970–33,457,544, forward strandZBTB9BAK1: 33,568,791–33,580,305, reverse strandBAK1ITPR3: 33,620,331–33,696,575, forward strandITPR3UQCC2: 33,690,635–33,711,748, reverse strandUQCC2IP6K3: 33,721,314–33,750,520, reverse strandIP6K3LEMD2: 33,771,202–33,789,173, reverse strandLEMD2MLN: 33,794,673–33,804,006, reverse strandMLNDiagram of ZBTB22: 2 exons on the reverse strand of chromosome 6Exon 2: 33,314,418–33,316,985, 2,568 basesExon 1: 33,317,653–33,317,744, 92 bases215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.7 kb of the gene's 3.3 kb; 1,905 of those bases code for the protein.

How a genome test reads ZBTB22

1

position in ZBTB22 where ClinVar classes a change as pathogenic or likely pathogenic

1 of them (100%) falls in a region short reads find hard.

  • MHC (1 site)The major histocompatibility complex (HLA genes), highly polymorphic and poorly represented by a single reference.

A whole genome covers all 3.3 kb of ZBTB22, introns included, not only the 2.7 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). ZBTB22 gene: zinc finger and BTB domain containing 22. Retrieved 17 October 2026, from https://dantelabs.com/genes/zbtb22

Vancouver

Dante Labs. ZBTB22 gene: zinc finger and BTB domain containing 22 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/zbtb22

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