Gene
WNT3
Wnt family member 3
- HGNC 12782↗(opens in a new tab)
- Ensembl gene ENSG00000108379↗(opens in a new tab)
- NCBI Gene 7473↗(opens in a new tab)
Summary
- Cytogenetic location
- 17q21.31-q21.32
- Coordinates
- Chromosome 17: 46,762,506–46,818,692 (GRCh38)
- Exons
- 5 exons across 56.2 kb
- Protein
- 355 amino acids
- Also known as
- MGC131950, MGC138321, MGC138323
- Previous symbols
- INT4
- MANE Select transcript
- ENST00000225512.6NM_030753.5
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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How WNT3 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 3.3 kb of the gene's 56.2 kb; 1,068 of those bases code for the protein.
Traits linked to WNT3
The Human Phenotype Ontology lists these as features of the rare conditions WNT3 can cause. Each trait's page lists the other genes linked to it.
Abnormality of head or neck
- Cleft of the mouth
- Decreased nasal size
- Blockage of the rear opening of the nasal cavity
- Cleft palate
- Cleft upper lip
- Full cheeks
- Little lower jaw
- Mono nostril
Show 2 more traits
Abnormality of the genitourinary system
- Absent external genitalia
- Abnormally closed or absent vagina
- Absent kidney
- Multicystic kidney dysplasia
- Smaller than typical growth of scrotum
- Underdeveloped fallopian tube
- Underdeveloped penis
- Undescended testes
Show 1 more trait
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
Cite this page
Dante Labs. (n.d.). WNT3 gene: Wnt family member 3. Retrieved 16 October 2026, from https://dantelabs.com/genes/wnt3
Dante Labs. WNT3 gene: Wnt family member 3 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/wnt3
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