Gene
STEAP3
STEAP3 metalloreductase
- HGNC 24592↗(opens in a new tab)
- Ensembl gene ENSG00000115107↗(opens in a new tab)
- NCBI Gene 55240↗(opens in a new tab)
Summary
- Cytogenetic location
- 2q14.2
- Coordinates
- Chromosome 2: 119,223,834–119,265,652 (GRCh38)
- Exons
- 6 exons across 41.8 kb
- Protein
- 498 amino acids
- Also known as
- TSAP6, dudlin-2, STMP3
- MANE Select transcript
- ENST00000393110.7NM_182915.3
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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How STEAP3 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 4.3 kb of the gene's 41.8 kb; 1,497 of those bases code for the protein.
Traits linked to STEAP3
The Human Phenotype Ontology lists these as features of the rare conditions STEAP3 can cause. Each trait's page lists the other genes linked to it.
Abnormality of blood and blood-forming tissues
- Hypochromia
- Low number of red blood cells or hemoglobin
- Poikilocytosis
- Reticulocytopenia
- Anisopoikilocytosis
- Decreased mean corpuscular volume
- Sideroblastic anemia
- Dysplastic erythropoesis
Show 1 more trait
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
Cite this page
Dante Labs. (n.d.). STEAP3 gene: STEAP3 metalloreductase. Retrieved 16 October 2026, from https://dantelabs.com/genes/steap3
Dante Labs. STEAP3 gene: STEAP3 metalloreductase [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/steap3
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