Traits

Traits linked to SERPINF1

serpin family F member 1

The Human Phenotype Ontology links 13 traits to SERPINF1, by body system: features seen in people with one of the gene's rare conditions.

Abnormality of the musculoskeletal system

Trait	How often it is seen
Compression fracture of a vertebral body	Always
Increased susceptibility to fractures	Always
Recurrent fractures	Always
Beaking of vertebral bodies	Not recorded
Biconcave vertebral bodies	Not recorded

Abnormality of limbs

Trait	How often it is seen
Bowed legs	Always
Bowing of the arm	Always
Abnormally indented hip sockets	Not recorded
Coxa vara	Not recorded

Laboratory abnormality

Trait	How often it is seen
Elevated alkaline phosphatase	Always
Elevated circulating deoxypyridinoline concentration	Always

Abnormality of the eye

Trait	How often it is seen
Blue outer white part of eyeball	Always

Abnormality of the nervous system

Trait	How often it is seen
Motor delay	Always

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the traits linked to SERPINF1 and how often each is seen. Find out more at hpo.jax.org.

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