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Gene

RHEB

Ras homolog, mTORC1 binding

Summary

Cytogenetic location
7q36.1
Coordinates
Chromosome 7: 151,466,012–151,519,895 (GRCh38)
Exons
8 exons across 53.9 kb
Protein
184 amino acids
Previous symbols
RHEB2
MANE Select transcript
ENST00000262187.10NM_005614.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads RHEB yet. The test sequences your whole genome, so your data includes it all the same.

How RHEB is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 7, with a bracket where RHEB sits. RHEB and 23 genes near it on chromosome 7, from 150,992,954 to 151,992,953.Chromosome 77q36.1p22.3p22.2p22.1p21.3p21.2p21.1p15.3p15.2p15.1p14.3p14.2p14.1p13p12.3p12.2p12.1p11.2p11.1q11.1q11.21q11.22q11.23q21.11q21.12q21.13q21.2q21.3q22.1q22.2q22.3q31.1q31.2q31.31q31.32q31.33q32.1q32.2q32.3q33q34q35q36.1q36.2q36.3151 Mb151.2 Mb151.4 Mb151.6 Mb151.8 MbNOS3: 150,991,017–151,015,653, forward strandNOS3ATG9B: 151,012,209–151,024,499, reverse strandATG9BABCB8: 151,028,422–151,047,782, forward strandASIC3: 151,048,292–151,052,756, forward strandCDK5: 151,051,517–151,057,952, reverse strandSLC4A2: 151,057,210–151,076,527, forward strandSLC4A2: 151,061,928–151,061,978, forward strandFASTK: 151,076,585–151,080,881, reverse strandFASTKTMUB1: 151,081,082–151,083,533, reverse strandTMUB1AGAP3: 151,085,831–151,144,450, forward strandAGAP3GBX1: 151,147,669–151,174,745, reverse strandGBX1ASB10: 151,175,684–151,187,832, reverse strandASB10DRC11L: 151,190,873–151,205,496, reverse strandH2BK1: 151,207,416–151,210,488, reverse strandABCF2-H2BK1: 151,207,837–151,227,166, reverse strandABCF2-H2BK1ABCF2: 151,211,484–151,227,264, reverse strandABCF2CHPF2: 151,232,483–151,240,979, forward strandCHPF2SMARCD3: 151,238,764–151,277,896, reverse strandSMARCD3NUB1: 151,341,704–151,381,097, forward strandNUB1WDR86: 151,375,909–151,410,727, reverse strandWDR86CRYGN: 151,428,293–151,440,813, reverse strandCRYGNRHEB: 151,466,012–151,519,895, reverse strandRHEBPRKAG2: 151,556,010–151,877,563, reverse strandPRKAG2GALNTL5: 151,956,379–152,019,929, forward strandGALNTL5Diagram of RHEB: 8 exons on the reverse strand of chromosome 7Exon 2: 1 known disease-causing siteExon 8: 151,466,012–151,467,211, 1,200 basesExon 7: 151,470,571–151,470,652, 82 basesExon 6: 151,471,394–151,471,441, 48 basesExon 5: 151,471,549–151,471,605, 57 basesExon 4: 151,477,333–151,477,415, 83 basesExon 3: 151,484,737–151,484,804, 68 basesExon 2: 151,490,943–151,491,014, 72 basesExon 1: 151,519,460–151,519,895, 436 bases864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2 kb of the gene's 53.9 kb; 555 of those bases code for the protein.

How a genome test reads RHEB

1

position in RHEB where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 53.9 kb of RHEB, introns included, not only the 2 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). RHEB gene: Ras homolog, mTORC1 binding. Retrieved 17 October 2026, from https://dantelabs.com/genes/rheb

Vancouver

Dante Labs. RHEB gene: Ras homolog, mTORC1 binding [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/rheb

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