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Gene

PAPSS2

3'-phosphoadenosine 5'-phosphosulfate synthase 2

Summary

Cytogenetic location
10q23.2-q23.31
Coordinates
Chromosome 10: 87,659,878–87,747,705 (GRCh38)
Exons
13 exons across 87.8 kb
Protein
619 amino acids
Also known as
ATPSK2
MANE Select transcript
ENST00000456849.2NM_001015880.2
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads PAPSS2 yet. The test sequences your whole genome, so your data includes it all the same.

How PAPSS2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 10, with a bracket where PAPSS2 sits. PAPSS2 and 7 genes near it on chromosome 10, from 87,203,792 to 88,203,791.Chromosome 1010q23.2-q23.31p15.3p15.2p15.1p14p13p12.33p12.32p12.31p12.2p12.1p11.23p11.22p11.21p11.1q11.1q11.21q11.22q11.23q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.31q23.32q23.33q24.1q24.2q24.31q24.32q24.33q25.1q25.2q25.3q26.11q26.12q26.13q26.2q26.387.4 Mb87.6 Mb87.8 Mb88 Mb88.2 MbNUTM2A: 87,225,448–87,236,908, forward strandNUTM2ANUTM2D: 87,357,720–87,370,695, forward strandNUTM2DMINPP1: 87,504,859–87,555,094, forward strandMINPP1PAPSS2: 87,659,878–87,747,705, forward strandPAPSS2ATAD1: 87,744,644–87,842,355, reverse strandATAD1KLLN: 87,859,158–87,863,533, reverse strandKLLNPTEN: 87,862,638–87,971,930, forward strandPTENMLDHR: 87,863,559–87,863,654, forward strandMLDHRDiagram of PAPSS2: 13 exons on the forward strand of chromosome 10Exon 2: 2 known disease-causing sitesExon 3: 2 known disease-causing sitesExon 4: 2 known disease-causing sitesExon 6: 3 known disease-causing sitesExon 7: 2 known disease-causing sitesExon 9: 4 known disease-causing sitesExon 10: 1 known disease-causing siteExon 11: 7 known disease-causing sitesExon 12: 2 known disease-causing sitesExon 13: 1 known disease-causing siteExon 1: 87,659,878–87,660,008, 131 basesExon 2: 87,709,196–87,709,313, 118 basesExon 3: 87,713,075–87,713,310, 236 basesExon 4: 87,714,044–87,714,182, 139 basesExon 5: 87,714,745–87,714,863, 119 basesExon 6: 87,714,985–87,715,098, 114 basesExon 7: 87,715,732–87,715,843, 112 basesExon 8: 87,721,756–87,721,770, 15 basesExon 9: 87,727,284–87,727,489, 206 basesExon 10: 87,741,235–87,741,370, 136 basesExon 11: 87,743,373–87,743,641, 269 basesExon 12: 87,745,002–87,745,231, 230 basesExon 13: 87,745,832–87,747,705, 1,874 bases1510135′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.7 kb of the gene's 87.8 kb; 1,860 of those bases code for the protein.

How a genome test reads PAPSS2

31

positions in PAPSS2 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 87.8 kb of PAPSS2, introns included, not only the 3.7 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). PAPSS2 gene: 3'-phosphoadenosine 5'-phosphosulfate synthase 2. Retrieved 17 October 2026, from https://dantelabs.com/genes/papss2

Vancouver

Dante Labs. PAPSS2 gene: 3'-phosphoadenosine 5'-phosphosulfate synthase 2 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/papss2

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