Gene
MRPS16
mitochondrial ribosomal protein S16
- HGNC 14048↗(opens in a new tab)
- Ensembl gene ENSG00000182180↗(opens in a new tab)
- NCBI Gene 51021↗(opens in a new tab)
Summary
- Cytogenetic location
- 10q22.2
- Coordinates
- Chromosome 10: 73,248,849–73,252,644 (GRCh38)
- Exons
- 3 exons across 3.8 kb
- Protein
- 137 amino acids
- Also known as
- CGI-132, bS16m
- MANE Select transcript
- ENST00000372945.8NM_016065.4
- Locus type
- Protein-coding
- Very high
- Confident
- Low
- Very low
This page as data
Add .json to the page's address, or ask for application/json, to read it as JSON.
library(jsonlite)
url <- "https://dantelabs.com/genes/mrps16.json"
page <- fromJSON(url)
page$gene$nameRead MRPS16, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome TestCurated reports relevant to this gene
No Genome Test report reads MRPS16 yet. The test sequences your whole genome, so your data includes it all the same.
How MRPS16 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 2.6 kb of the gene's 3.8 kb; 414 of those bases code for the protein.
Sequencing MRPS16
3Low
How hard MRPS16 is to sequence with short reads, out of 100Each bar is the share of MRPS16's exon bases in that kind of difficult region. The score weighs them by how much each costs a short-read call: 0 when no base is in any, 100 when every base is in all of them.
- MappabilityStretches where 100 or 250 bp reads cannot be placed uniquely, so a call there may be missing or wrong. Weight 35%.0%
- HomologySegmental duplications: copies elsewhere in the genome, such as paralogues and pseudogenes, at 90% identity or more. Weight 30%.0%
- RepeatsTandem repeats and runs of one base, which reads slip on and may not span. Weight 15%.15%
- GC contentWindows under 25% or over 65% G and C, which library preparation covers thinly. Weight 10%.5.2%
- Reference coverageGaps in the reference assembly nearby, where there is no sequence for reads to align to. Weight 10%.0%
1
position in MRPS16 where ClinVar classes a change as pathogenic or likely pathogenic
None of them falls in a region short reads find hard.
A whole genome covers all 3.8 kb of MRPS16, introns included, not only the 2.6 kb of exons.
Traits linked to MRPS16
The Human Phenotype Ontology lists these as features of the rare conditions MRPS16 can cause. Each trait's page lists the other genes linked to it.
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
- The Genome in a Bottle genome stratifications, from NIST: the sequencing difficulty score.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
- Data release 2026.10.17-8666dff2.
Cite this page
Dante Labs. (n.d.). MRPS16 gene: mitochondrial ribosomal protein S16. Retrieved 17 October 2026, from https://dantelabs.com/genes/mrps16
Dante Labs. MRPS16 gene: mitochondrial ribosomal protein S16 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/mrps16
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks