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Gene

GRIA4

glutamate ionotropic receptor AMPA type subunit 4

Summary

Cytogenetic location
11q22.3
Coordinates
Chromosome 11: 105,610,073–105,982,090 (GRCh38)
Exons
17 exons across 372 kb
Protein
902 amino acids
Also known as
GluA4, GLURD, GluR-4, GluR-D, GLUR4C
Previous symbols
GLUR4
MANE Select transcript
ENST00000282499.10NM_000829.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads GRIA4 yet. The test sequences your whole genome, so your data includes it all the same.

How GRIA4 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 11, with a bracket where GRIA4 sits. GRIA4 and 4 genes near it on chromosome 11, from 105,238,055 to 106,354,108.Chromosome 1111q22.3p15.5p15.4p15.3p15.2p15.1p14.3p14.2p14.1p13p12p11.2p11.12p11.11q11q12.1q12.2q12.3q13.1q13.2q13.3q13.4q13.5q14.1q14.2q14.3q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q25105.4 Mb105.6 Mb105.8 Mb106 Mb106.2 MbCARD18: 105,137,714–105,531,697, reverse strandCARD18GRIA4: 105,610,073–105,982,090, forward strandGRIA4MSANTD4: 105,995,623–106,022,410, reverse strandMSANTD4KBTBD3: 106,047,228–106,077,459, reverse strandKBTBD3AASDHPPT: 106,075,501–106,098,708, forward strandAASDHPPTDiagram of GRIA4: 17 exons on the forward strand of chromosome 11Exon 5: 1 known disease-causing siteExon 13: 1 known disease-causing siteExon 14: 1 known disease-causing siteExon 1: 105,610,073–105,610,428, 356 basesExon 2: 105,610,908–105,611,085, 178 basesExon 3: 105,612,276–105,612,434, 159 basesExon 4: 105,752,981–105,753,220, 240 basesExon 5: 105,862,024–105,862,208, 185 basesExon 6: 105,887,519–105,887,572, 54 basesExon 7: 105,898,269–105,898,427, 159 basesExon 8: 105,903,814–105,903,981, 168 basesExon 9: 105,905,197–105,905,301, 105 basesExon 10: 105,910,435–105,910,545, 111 basesExon 11: 105,918,712–105,918,918, 207 basesExon 12: 105,924,399–105,924,769, 371 basesExon 13: 105,926,741–105,926,939, 199 basesExon 14: 105,933,722–105,933,969, 248 basesExon 15: 105,971,914–105,972,028, 115 basesExon 16: 105,974,310–105,974,444, 135 basesExon 17: 105,979,575–105,982,090, 2,516 bases151015175′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 5.5 kb of the gene's 372 kb; 2,709 of those bases code for the protein.

How a genome test reads GRIA4

3

positions in GRIA4 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 372 kb of GRIA4, introns included, not only the 5.5 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). GRIA4 gene: glutamate ionotropic receptor AMPA type subunit 4. Retrieved 17 October 2026, from https://dantelabs.com/genes/gria4

Vancouver

Dante Labs. GRIA4 gene: glutamate ionotropic receptor AMPA type subunit 4 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/gria4

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