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Gene

FYCO1

FYVE and coiled-coil domain autophagy adaptor 1

Summary

Cytogenetic location
3p21.31
Coordinates
Chromosome 3: 45,917,903–45,995,824 (GRCh38)
Exons
18 exons across 77.9 kb
Protein
1,478 amino acids
Also known as
FLJ13335, ZFYVE7
MANE Select transcript
ENST00000296137.7NM_024513.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads FYCO1 yet. The test sequences your whole genome, so your data includes it all the same.

How FYCO1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 3, with a bracket where FYCO1 sits. FYCO1 and 14 genes near it on chromosome 3, from 45,456,864 to 46,456,863.Chromosome 33p21.31p26.3p26.2p26.1p25.3p25.2p25.1p24.3p24.2p24.1p23p22.3p22.2p22.1p21.33p21.32p21.31p21.2p21.1p14.3p14.2p14.1p13p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12.1q12.2q12.3q13.11q13.12q13.13q13.2q13.31q13.32q13.33q21.1q21.2q21.3q22.1q22.2q22.3q23q24q25.1q25.2q25.31q25.32q25.33q26.1q26.2q26.31q26.32q26.33q27.1q27.2q27.3q28q2945.6 Mb45.8 Mb46 Mb46.2 Mb46.4 MbLARS2: 45,388,516–45,554,726, forward strandLARS2LIMD1: 45,555,394–45,686,341, forward strandLIMD1SACM1L: 45,689,056–45,745,425, forward strandSACM1LSLC6A20: 45,748,903–45,796,654, reverse strandSLC6A20LZTFL1: 45,823,316–45,916,042, reverse strandLZTFL1CCR9: 45,884,425–45,904,311, forward strandCCR9FYCO1: 45,917,903–45,995,824, reverse strandFYCO1CXCR6: 45,940,915–45,948,640, forward strandCXCR6XCR1: 46,016,988–46,085,850, reverse strandXCR1CCR3: 46,130,890–46,266,717, forward strandCCR3CCR1: 46,201,709–46,208,676, reverse strandCCR1CCR2: 46,353,864–46,360,940, forward strandCCR2CCR5: 46,370,939–46,377,528, forward strandCCR5CCRL2: 46,407,144–46,412,997, forward strandCCRL2LTF: 46,434,347–46,485,234, reverse strandLTFDiagram of FYCO1: 18 exons on the reverse strand of chromosome 3Exon 14: 1 known disease-causing siteExon 12: 1 known disease-causing siteExon 11: 4 known disease-causing sitesExon 10: 1 known disease-causing siteExon 8: 12 known disease-causing sitesExon 7: 1 known disease-causing siteExon 6: 3 known disease-causing sitesExon 4: 2 known disease-causing sitesExon 18: 45,917,903–45,921,840, 3,938 basesExon 17: 45,923,656–45,923,765, 110 basesExon 16: 45,931,071–45,931,281, 211 basesExon 15: 45,936,448–45,936,543, 96 basesExon 14: 45,955,249–45,955,393, 145 basesExon 13: 45,958,408–45,958,619, 212 basesExon 12: 45,959,393–45,959,542, 150 basesExon 11: 45,962,225–45,962,392, 168 basesExon 10: 45,964,336–45,964,454, 119 basesExon 9: 45,965,033–45,965,125, 93 basesExon 8: 45,966,277–45,968,703, 2,427 basesExon 7: 45,969,675–45,969,765, 91 basesExon 6: 45,973,088–45,973,231, 144 basesExon 5: 45,975,239–45,975,345, 107 basesExon 4: 45,979,705–45,979,830, 126 basesExon 3: 45,981,570–45,981,676, 107 basesExon 2: 45,984,856–45,985,022, 167 basesExon 1: 45,995,722–45,995,824, 103 bases1816141210864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 8.5 kb of the gene's 77.9 kb; 4,437 of those bases code for the protein.

How a genome test reads FYCO1

28

positions in FYCO1 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 77.9 kb of FYCO1, introns included, not only the 8.5 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). FYCO1 gene: FYVE and coiled-coil domain autophagy adaptor 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/fyco1

Vancouver

Dante Labs. FYCO1 gene: FYVE and coiled-coil domain autophagy adaptor 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/fyco1

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