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Gene

CCR2

C-C motif chemokine receptor 2

Summary

Cytogenetic location
3p21.31
Coordinates
Chromosome 3: 46,354,111–46,360,940 (GRCh38)
Exons
2 exons across 6.8 kb
Protein
360 amino acids
Also known as
CC-CKR-2, CKR2, MCP-1-R, CD192, FLJ78302
Previous symbols
CMKBR2
MANE Select transcript
ENST00000445132.3NM_001123396.4
Locus type
Protein-coding
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads CCR2 yet. The test sequences your whole genome, so your data includes it all the same.

How CCR2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
Chromosome 3, with a bracket where CCR2 sits. CCR2 and 20 genes near it on chromosome 3, from 45,857,526 to 46,857,525.Chromosome 33p21.31p26.3p26.2p26.1p25.3p25.2p25.1p24.3p24.2p24.1p23p22.3p22.2p22.1p21.33p21.32p21.31p21.2p21.1p14.3p14.2p14.1p13p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12.1q12.2q12.3q13.11q13.12q13.13q13.2q13.31q13.32q13.33q21.1q21.2q21.3q22.1q22.2q22.3q23q24q25.1q25.2q25.31q25.32q25.33q26.1q26.2q26.31q26.32q26.33q27.1q27.2q27.3q28q2946 Mb46.2 Mb46.4 Mb46.6 Mb46.8 MbLZTFL1: 45,823,316–45,916,042, reverse strandLZTFL1CCR9: 45,884,425–45,904,311, forward strandCCR9FYCO1: 45,917,903–45,995,845, reverse strandFYCO1CXCR6: 45,940,915–45,948,640, forward strandCXCR6XCR1: 46,016,988–46,085,850, reverse strandXCR1CCR3: 46,130,890–46,266,717, forward strandCCR3CCR1: 46,201,709–46,208,676, reverse strandCCR1CCR2: 46,354,111–46,360,940, forward strandCCR2CCR5: 46,370,939–46,377,528, forward strandCCR5CCRL2: 46,407,144–46,412,997, forward strandCCRL2LTF: 46,434,347–46,485,234, reverse strandLTFRTP3: 46,494,611–46,501,506, forward strandRTP3LRRC2: 46,510,358–46,607,097, reverse strandLRRC2CRIPTO: 46,573,633–46,584,684, forward strandCRIPTO: 46,581,150–46,617,226, forward strandFAM240A: 46,612,525–46,626,543, forward strandFAM240AALS2CL: 46,668,994–46,694,071, reverse strandALS2CLTMIE: 46,694,528–46,710,886, forward strandTMIE: 46,712,115–46,812,574, reverse strandPRSS50: 46,712,117–46,717,869, reverse strandPRSS50MYL3: 46,835,109–46,885,911, reverse strandMYL3Diagram of CCR2: 2 exons on the forward strand of chromosome 3Exon 2: 1 known disease-causing siteExon 1: 46,354,111–46,354,177, 67 basesExon 2: 46,357,477–46,360,940, 3,464 bases125′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.5 kb of the gene's 6.8 kb; 1,083 of those bases code for the protein.

Sequencing CCR2

1

position in CCR2 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 6.8 kb of CCR2, introns included, not only the 3.5 kb of exons.

ClinVar pathogenic variants (1)

The CCR2 variants ClinVar classifies pathogenic or likely pathogenic for any condition, reviewed by at least one submitter with criteria, and the most reviewed of them. It is ClinVar's public record of the gene, never a result.

  • Likely pathogenic 1
VariantConditionsClinVar classificationReview status
NM_001123396.4(CCR2):c.586C>T (p.Arg196Ter) (opens in a new tab)cystic disease of lungLikely pathogenic1 star out of 4 criteria provided, single submitter

Traits linked to CCR2

The Human Phenotype Ontology lists these as features of the rare conditions CCR2 can cause. Each trait's page lists the other genes linked to it.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.18-8b139e39.

Cite this page

APA

Dante Labs. (n.d.). CCR2 gene: C-C motif chemokine receptor 2. Retrieved 19 October 2026, from https://dantelabs.com/genes/ccr2

Vancouver

Dante Labs. CCR2 gene: C-C motif chemokine receptor 2 [Internet]. [cited 19 October 2026]. Available from: https://dantelabs.com/genes/ccr2

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