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Gene

EPS15L1

epidermal growth factor receptor pathway substrate 15 like 1

Summary

Cytogenetic location
19p13.11
Coordinates
Chromosome 19: 16,355,247–16,471,970 (GRCh38)
Exons
24 exons across 116.7 kb
Protein
910 amino acids
Also known as
eps15R
MANE Select transcript
ENST00000455140.7NM_001258374.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads EPS15L1 yet. The test sequences your whole genome, so your data includes it all the same.

How EPS15L1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 19, with a bracket where EPS15L1 sits. EPS15L1 and 22 genes near it on chromosome 19, from 15,913,609 to 16,913,608.Chromosome 1919p13.11p13.3p13.2p13.13p13.12p13.11p12p11q11q12q13.11q13.12q13.13q13.2q13.31q13.32q13.33q13.41q13.42q13.4316 Mb16.2 Mb16.4 Mb16.6 Mb16.8 MbCYP4F11: 15,912,367–15,934,933, reverse strandCYP4F11OR10H4: 15,944,299–15,950,350, forward strandOR10H4TPM4: 16,067,021–16,103,011, forward strandTPM4RAB8A: 16,111,653–16,134,235, forward strandRAB8AHSH2D: 16,134,028–16,158,575, forward strandHSH2DCIB3: 16,161,368–16,173,525, reverse strandCIB3FAM32A: 16,185,378–16,192,048, forward strandFAM32AAP1M1: 16,197,854–16,245,906, forward strandAP1M1KLF2: 16,324,613–16,328,685, forward strandKLF2EPS15L1: 16,355,247–16,471,970, reverse strandEPS15L1CALR3: 16,479,061–16,496,167, reverse strandCALR3: 16,479,067–16,628,204, reverse strandC19orf44: 16,496,385–16,521,369, forward strandC19orf44CHERP: 16,517,882–16,542,547, reverse strandCHERPSLC35E1: 16,549,831–16,572,432, reverse strandSLC35E1MED26: 16,574,907–16,629,062, reverse strandMED26: 16,577,642–16,660,115, reverse strandSMIM7: 16,630,744–16,660,442, reverse strandSMIM7TMEM38A: 16,660,370–16,690,041, forward strandTMEM38ANWD1: 16,719,847–16,817,963, forward strandNWD1SIN3B: 16,829,387–16,880,355, forward strandSIN3BF2RL3: 16,888,844–16,892,606, forward strandF2RL3CPAMD8: 16,892,951–17,026,982, reverse strandCPAMD8Diagram of EPS15L1: 24 exons on the reverse strand of chromosome 19Exon 24: 16,355,247–16,355,851, 605 basesExon 23: 16,361,779–16,361,984, 206 basesExon 22: 16,377,122–16,377,254, 133 basesExon 21: 16,385,129–16,385,211, 83 basesExon 20: 16,386,171–16,386,231, 61 basesExon 19: 16,392,304–16,392,440, 137 basesExon 18: 16,393,951–16,394,001, 51 basesExon 17: 16,395,344–16,395,467, 124 basesExon 16: 16,402,321–16,402,485, 165 basesExon 15: 16,403,733–16,403,930, 198 basesExon 14: 16,404,588–16,404,749, 162 basesExon 13: 16,413,773–16,413,845, 73 basesExon 12: 16,417,552–16,417,637, 86 basesExon 11: 16,417,948–16,418,104, 157 basesExon 10: 16,421,319–16,421,476, 158 basesExon 9: 16,425,083–16,425,316, 234 basesExon 8: 16,428,702–16,428,761, 60 basesExon 7: 16,434,365–16,434,490, 126 basesExon 6: 16,436,937–16,436,999, 63 basesExon 5: 16,437,770–16,437,865, 96 basesExon 4: 16,440,862–16,440,909, 48 basesExon 3: 16,441,892–16,441,981, 90 basesExon 2: 16,442,178–16,442,219, 42 basesExon 1: 16,471,913–16,471,970, 58 bases24201510515′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.2 kb of the gene's 116.7 kb; 2,733 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.

Cite this page

APA

Dante Labs. (n.d.). EPS15L1 gene: epidermal growth factor receptor pathway substrate 15 like 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/eps15l1

Vancouver

Dante Labs. EPS15L1 gene: epidermal growth factor receptor pathway substrate 15 like 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/eps15l1

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