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Trait

Persistent fetal circulation

Systemic desaturation of a liveborn baby resulting from persistent pulmonary hypertension with a patent ductus arteriosus and patent foramen ovale, such that the circulation in postnatal life follows the fetal course.

HPO HP:0011726

Summary

Also called
Persistent foetal circulation
Body system
Abnormality of prenatal development or birthAbnormality of the cardiovascular system

1 gene linked to Persistent fetal circulation

Changes in these genes cause rare conditions in which Persistent fetal circulation is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

GeneHow often it is seenConditions
UQCRFS1ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1Often (30–79%)In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Abnormal fetal cardiovascular physiology

Where this comes from

  • The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
  • Data release 2026.10.17-8666dff2.

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