Trait

Mitral valve calcification

Abnormal calcification of the mitral valve.

Body system: Abnormality of the cardiovascular system Abnormality of the musculoskeletal system

This page as data

Add .json to the page's address, or ask for application/json, to read it as JSON.

library(jsonlite)

url <- "https://dantelabs.com/traits/mitral-valve-calcification.json"
page <- fromJSON(url)
page$trait$name

Open the JSON

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7 genes linked to Mitral valve calcification

Changes in these genes cause rare conditions in which Mitral valve calcification is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
LMNAlamin A/C	Very often (80–99%)	In 2 conditions
GBA1glucosylceramidase beta 1	Often (30–79%)	In 3 conditions
HGDhomogentisate 1,2-dioxygenase	Often (30–79%)	In 2 conditions
MTX2metaxin 2	Sometimes (5–29%)	In 1 condition
ZMPSTE24zinc metallopeptidase STE24	Sometimes (5–29%)	In 1 condition
SLC34A2solute carrier family 34 member 2	Rarely (1–4%)	In 1 condition
IFIH1interferon induced with helicase C domain 1	Not recorded	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Narrower traits

Mitral annular calcification1 gene

Broader traits

Abnormal mitral valve morphology Cardiac valve calcification

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.16-c6eea6bf.

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