Trait

Elevated circulating thyroglobulin concentration

The concentration of thyroglobulin in the blood circulation is above the upper limit of normal.

Also called: Elevated thyroglobulin concentration, Elevated thyroglobulin level, Elevated thyroglobulin level in blood, Increased circulating thyroglobulin level, Increased thyroglobulin concentration, Increased thyroglobulin level, Increased thyroglobulin level in blood
Body system: Laboratory abnormality

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page$trait$name

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9 genes linked to Elevated circulating thyroglobulin concentration

Changes in these genes cause rare conditions in which Elevated circulating thyroglobulin concentration is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
GLIS3GLIS family zinc finger 3	Always	In 1 condition
THRBthyroid hormone receptor beta	Always	In 2 conditions
TSHRthyroid stimulating hormone receptor	Always	In 2 conditions
DUOX2dual oxidase 2	Often (30–79%)	In 1 condition
FOXI1forkhead box I1	Often (30–79%)	In 1 condition
KCNJ10potassium inwardly rectifying channel subfamily J member 10	Often (30–79%)	In 1 condition
PAX8paired box 8	Often (30–79%)	In 1 condition
SLC26A4solute carrier family 26 member 4	Often (30–79%)	In 1 condition
SLC35A2solute carrier family 35 member A2	Rarely (1–4%)	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Abnormal circulating thyroglobulin concentration

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.16-c6eea6bf.

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