Trait
Cloverleaf cranium shape
Clinical name: Cloverleaf skull
Trilobar skull configuration when viewed from the front or behind.
Summary
- Also called
- Cloverleaf skull shape, Kleeblattschaedel
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Get my Genome Test8 genes linked to Cloverleaf cranium shape
Changes in these genes cause rare conditions in which Cloverleaf cranium shape is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| FGFR2fibroblast growth factor receptor 2 | Always | In 5 conditions |
| FGFR3fibroblast growth factor receptor 3 | Always | In 4 conditions |
| EXTL3exostosin like glycosyltransferase 3 | Often (30–79%) | In 2 conditions |
| MEGF8multiple EGF like domains 8 | Often (30–79%) | In 1 condition |
| RAB23RAB23, member RAS oncogene family | Often (30–79%) | In 1 condition |
| FGFR1fibroblast growth factor receptor 1 | Sometimes (5–29%) | In 2 conditions |
| PORcytochrome p450 oxidoreductase | Not recorded | In 1 condition |
| WDR35WD repeat domain 35 | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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