Trait
Ankle hypermobility
The ankle joint can move, passively and/or actively, beyond normal limits along its physiological axes.
Summary
- Also called
- Increased laxity of ankles
Reference genomeGRCh38hg38
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Get my Genome Test5 genes linked to Ankle hypermobility
Changes in these genes cause rare conditions in which Ankle hypermobility is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| MFN2mitofusin 2 | Often (30–79%) | In 1 condition |
| COMPcartilage oligomeric matrix protein | Sometimes (5–29%) | In 1 condition |
| GLI3GLI family zinc finger 3 | Sometimes (5–29%) | In 1 condition |
| PYCR2pyrroline-5-carboxylate reductase 2 | Sometimes (5–29%) | In 1 condition |
| COL6A1collagen type VI alpha 1 chain | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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