Skip to content
Use your HSA or FSA funds

Trait

Accelerated ankle bone maturation

Clinical name: Advanced tarsal ossification

Precocious (accelerated) maturation and calcification of any of the tarsal bones, seven bones of the foot comprising the calcaneus, talus, cuboid, navicular, and the cuneiform bones.

HPO HP:0008108

Summary

Also called
Precociously ossified tarsal bones
Body system
Abnormality of limbsAbnormality of the musculoskeletal system

4 genes linked to Accelerated ankle bone maturation

Changes in these genes cause rare conditions in which Accelerated ankle bone maturation is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

GeneHow often it is seenConditions
INPPL1inositol polyphosphate phosphatase like 1Sometimes (5–29%)In 1 condition
SLC35D1solute carrier family 35 member D1Sometimes (5–29%)In 2 conditions
CANT1calcium activated nucleotidase 1Not recordedIn 1 condition
PTH1Rparathyroid hormone 1 receptorNot recordedIn 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Abnormal maturation of ankle bones

Where this comes from

  • The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test