30X SEQUENCING · HSA/FSA ELIGIBLE
Whole Genome Sequencing
The complete picture of your genetic health.
Whole genome sequencing reads nearly all of your DNA, not a preset sample of it. Every kit includes trait reports, and Premium adds 810+ physician-ready reports.
90+ condition and wellness reports and 20+ polygenic risk scores included. 760+ condition and wellness reports and 40+ polygenic risk scores with Premium: $99 for the first year, then $99 a year.
HSA/FSA eligible
HSA/FSA eligible · Free shipping with a prepaid return label · Reports typically in 6 to 8 weeks
What's Included
Everything in Your Whole Genome Sequencing Kit
Included with every kit. Add 810+ physician-ready reports with Premium.
Explore your reports and share them with your doctor.
Each position read about 30 times on average.
Download your FASTQ, BAM and VCF files, or request deletion, anytime.
Questions about the kit? Read the FAQ
How it works
Whole Genome Sequencing vs. Genotyping and Exome Tests
Think of your DNA as an instruction manual for your body, written in about 6.4 billion letters called base pairs: two copies of about 3.2 billion, one from each parent. Whole genome sequencing reads nearly every letter, about 30 times on average, so the lab can confirm its calls.
Consumer DNA tests like 23andMe and AncestryDNA spot-check 600,000 to 700,000 letters chosen in advance. Exome tests read only the sections that build proteins, about 1% of the manual.
Share of your genome read
600,000–700,000
letters, chosen in advance
How it works
Spot-checks a preset list of positions, so anything off the list is never read.
Share of your genome read
About 1%
of your genome: the sections that build proteins
How it works
Reads the protein-coding sections and leaves the rest of the genome unread.
Share of your genome read
6.4 billion
letters, each read about 30 times on average
How it works
Reads nearly every letter, so the lab can confirm its calls. 99.98% accuracy across 100,000+ genomes.
Exome figure: MedlinePlus
For yourself, or for someone you care for
Who Whole Genome Sequencing Helps
You want to know before something forces the question.
Proactive HealthIt runs in your family. Now you can know if it runs in your genes.
Hereditary RiskWhen traditional lab tests say you're fine. And you know you're not.
Unexplained SymptomsYour diagnosis may be right. Your treatment plan may be incomplete.
Treatment Not Working
One sequence, read many ways
What Whole Genome Sequencing Tells You
- NutrigeneticsTwelve loci across four chapters where your genome shapes how you eat, absorb, and process from caffeine and alcohol to vitamins, fats, and taste.
- Sleep & ChronotypeTen loci across four chapters that shape when your body wants to sleep, how deeply it rests, how long it needs, and what disrupts it — from the circadian clock to adenosine and the genetics of sleep duration.
- Sports & PerformanceThirteen loci across four chapters that shape how your body responds to training — from explosive power and the aerobic engine to injury resilience, recovery, and adaptation.
Each condition finding names the variant, its gene and its classification under ACMG standards, in a portal you can share with your doctor.
One genome, three plans
Whole Genome Sequencing Plans
Every plan includes your genome kit, sequenced at 30X and shipped free with a prepaid return label.
Included
Core
$449
One-time kit
- 30X whole genome
- Trait reports and ancestry
- Raw data and the Genome Manager
Premium
$548
First year, kit included
- Everything in Core
- 810+ physician-ready reports
- Monthly genetic insights
With AI
Premium + AI
$649
First year, kit included
- Everything in Premium
- Ask Dante
- MCP access
HSA/FSA eligible. How plans work
In their words
Why They Chose Whole Genome Sequencing
A family history of cancer, a diagnosis no one could explain, a family on the way. Hear why they read their whole genome, not a sample of it.
Accredited sequencing and reporting
Clinical-Grade Whole Genome Sequencing Lab
Genomes sequenced
Accuracy across 100,000+ genomes
Clinical reports generated
The process · No clinic visit required
Four Steps to Whole Genome Sequencing
Order your kit
Free delivery worldwide.
Collect your sample
Simple finger-prick blood spot collection at home. Takes 5 minutes. Everything you need is in the kit.
Send it back
Pre-paid return label included. Drop it in any post box.
Access your results
Reports delivered to your Genome Manager in 6–8 weeks. Review every finding and share directly with your physician.
Comparing tests
How Dante Labs Compares
Side-by-side comparisons with other genetic tests, with sources.
Still have a question?
Whole Genome Sequencing FAQ
Your data is yours.
It reads nearly your complete DNA sequence, about 6.4 billion base pairs across your two copies, instead of a preset list of positions or genes. At 30X depth, that data becomes reports you can share with your doctor. For the basics, see the DNA sequencing fact sheet from the National Human Genome Research Institute.
The price for your country is shown, in your currency, at checkout. It includes 30X sequencing, 810+ reports, lifetime Genome Manager access, automatic updates, and free worldwide shipping.
810+ physician-ready reports cover cardiac conditions, hereditary cancer, neurological conditions, rare diseases, and pharmacogenomics, delivered through the Genome Manager portal.
WES reads only protein-coding regions (1–2% of DNA). WGS reads all 6.4 billion base pairs including regulatory and intergenic regions, making it more comprehensive.
Consumer tests use genotyping, reading less than 0.02% of your genome. Dante sequences the full genome at 30X clinical coverage, identifying 4.6–5 million variants including rare variants and structural changes.
30X coverage means that, on average, every position in your genome is read 30 times. This ensures 99.98% accuracy and is the clinical diagnostic standard.
Whole genome results typically arrive in 6–8 weeks after lab arrival, with email updates at each processing step.
No. Whole genome sequencing is available direct-to-consumer without prescription or referral, though discussing results with healthcare professionals is recommended.
You do. You control your data—download, delete, or anonymize anytime. Dante doesn’t sell personal information or genomic data.
Sequence once
Start Your Whole Genome Sequencing
With an active Premium plan, reports update as new variant-disease connections are validated. How report updates work
Free shipping · HSA/FSA eligible · GDPR protected