Skip to content
Use your HSA or FSA funds

Gene

WDR74

WD repeat domain 74

Summary

Cytogenetic location
11q12.3
Coordinates
Chromosome 11: 62,832,911–62,839,590 (GRCh38)
Exons
11 exons across 6.7 kb
Protein
385 amino acids
Also known as
FLJ10439, Nsa1
MANE Select transcript
ENST00000278856.9NM_001369450.1
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads WDR74 yet. The test sequences your whole genome, so your data includes it all the same.

How WDR74 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
Chromosome 11, with a bracket where WDR74 sits. WDR74 and 41 genes near it on chromosome 11, from 62,336,251 to 63,336,250.Chromosome 1111q12.3p15.5p15.4p15.3p15.2p15.1p14.3p14.2p14.1p13p12p11.2p11.12p11.11q11q12.1q12.2q12.3q13.1q13.2q13.3q13.4q13.5q14.1q14.2q14.3q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q2562.4 Mb62.6 Mb62.8 Mb63 Mb63.2 MbASRGL1: 62,337,347–62,393,415, forward strandASRGL1SCGB1A1: 62,405,103–62,423,195, forward strandSCGB1A1AHNAK: 62,433,532–62,556,235, reverse strandAHNAKEEF1G: 62,559,593–62,574,086, reverse strand: 62,559,603–62,591,531, reverse strandTUT1: 62,575,045–62,591,637, reverse strandMTA2: 62,593,214–62,601,927, reverse strandMTA2EML3: 62,602,216–62,612,978, reverse strandEML3ROM1: 62,611,722–62,615,116, forward strandROM1B3GAT3: 62,614,993–62,622,180, reverse strandB3GAT3GANAB: 62,624,821–62,646,726, reverse strandINTS5: 62,646,848–62,653,316, reverse strand: 62,649,694–62,665,178, reverse strandC11orf98: 62,662,815–62,665,251, reverse strandLBHD1: 62,662,817–62,672,284, reverse strandCSKMT: 62,665,309–62,668,496, forward strandUQCC3: 62,670,273–62,674,001, forward strandUBXN1: 62,676,498–62,679,332, reverse strandUBXN1LRRN4CL: 62,686,406–62,689,609, reverse strandBSCL2: 62,689,289–62,709,861, reverse strandHNRNPUL2-BSCL2: 62,690,275–62,727,384, reverse strandGNG3: 62,706,400–62,712,083, forward strandHNRNPUL2: 62,712,630–62,727,637, reverse strand: 62,726,885–62,727,265, reverse strandTTC9C: 62,727,687–62,740,293, forward strandTTC9CZBTB3: 62,737,172–62,758,835, reverse strandZBTB3POLR2G: 62,761,453–62,766,715, forward strandPOLR2GTAF6L: 62,771,307–62,787,342, forward strandTAF6LTMEM223: 62,771,629–62,792,022, reverse strandTMEM179B: 62,787,375–62,792,166, forward strandNXF1: 62,792,123–62,806,302, reverse strandSTX5: 62,806,860–62,832,076, reverse strandSTX5TEX54: 62,832,321–62,832,841, reverse strandTEX54WDR74: 62,832,911–62,839,590, reverse strandWDR74RNU2-2: 62,841,619–62,841,809, reverse strandRNU2-2SLC3A2: 62,855,970–62,888,910, forward strandSLC3A2CHRM1: 62,907,828–62,921,877, reverse strandCHRM1SLC22A6: 62,936,385–62,984,973, reverse strandSLC22A6SLC22A8: 62,989,154–63,017,561, reverse strandSLC22A8SLC22A24: 63,077,406–63,144,221, reverse strandSLC22A24SLC22A25: 63,158,437–63,243,788, reverse strandSLC22A25SLC22A10: 63,268,022–63,311,874, forward strandSLC22A10Diagram of WDR74: 11 exons on the reverse strand of chromosome 11Exon 11: 62,832,911–62,833,131, 221 basesExon 10: 62,833,618–62,833,674, 57 basesExon 9: 62,833,792–62,833,937, 146 basesExon 8: 62,834,276–62,834,331, 56 basesExon 7: 62,834,427–62,834,527, 101 basesExon 6: 62,835,431–62,835,532, 102 basesExon 5: 62,835,695–62,835,841, 147 basesExon 4: 62,835,961–62,836,036, 76 basesExon 3: 62,839,114–62,839,235, 122 basesExon 2: 62,839,322–62,839,428, 107 basesExon 1: 62,839,507–62,839,590, 84 bases11109876543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.2 kb of the gene's 6.7 kb; 1,158 of those bases code for the protein.

How a genome test reads WDR74

2

positions in WDR74 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 6.7 kb of WDR74, introns included, not only the 1.2 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). WDR74 gene: WD repeat domain 74. Retrieved 17 October 2026, from https://dantelabs.com/genes/wdr74

Vancouver

Dante Labs. WDR74 gene: WD repeat domain 74 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/wdr74

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test