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Gene

VAMP2

vesicle associated membrane protein 2

Summary

Cytogenetic location
17p13.1
Coordinates
Chromosome 17: 8,159,149–8,162,948 (GRCh38)
Exons
5 exons across 3.8 kb
Protein
116 amino acids
Also known as
VAMP-2
Previous symbols
SYB2
MANE Select transcript
ENST00000316509.11NM_014232.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads VAMP2 yet. The test sequences your whole genome, so your data includes it all the same.

How VAMP2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
Chromosome 17, with a bracket where VAMP2 sits. VAMP2 and 36 genes near it on chromosome 17, from 7,661,049 to 8,661,048.Chromosome 1717p13.1p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.37.8 Mb8 Mb8.2 Mb8.4 Mb8.6 MbTP53: 7,661,779–7,687,546, reverse strandTP53WRAP53: 7,686,071–7,703,505, forward strandWRAP53EFNB3: 7,705,172–7,711,372, forward strandEFNB3DNAH2: 7,717,728–7,833,742, forward strandDNAH2KDM6B: 7,834,193–7,854,808, forward strandKDM6BTMEM88: 7,855,057–7,856,114, forward strandTMEM88NAA38: 7,856,681–7,885,238, reverse strandNAA38CYB5D1: 7,857,696–7,862,282, forward strandCYB5D1CHD3: 7,884,787–7,912,760, forward strandRNF227: 7,913,238–7,916,377, reverse strandKCNAB3: 7,920,956–7,929,856, reverse strandKCNAB3: 7,925,931–7,930,622, reverse strandTRAPPC1: 7,930,345–7,932,123, reverse strandTRAPPC1CNTROB: 7,932,101–7,949,953, forward strandCNTROBGUCY2D: 8,002,615–8,020,342, forward strandGUCY2DALOX15B: 8,039,011–8,049,134, forward strandALOX15BALOX12B: 8,068,594–8,087,716, reverse strandALOX12BALOXE3: 8,095,900–8,119,047, reverse strandALOXE3HES7: 8,120,592–8,124,114, reverse strandHES7PER1: 8,140,467–8,156,506, reverse strandPER1: 8,150,816–8,162,975, reverse strandVAMP2: 8,159,149–8,162,948, reverse strandVAMP2TMEM107: 8,172,440–8,176,408, reverse strandTMEM107BORCS6: 8,188,345–8,190,180, reverse strandAURKB: 8,204,335–8,210,638, reverse strandAURKBCTC1: 8,224,815–8,248,075, reverse strandCTC1PFAS: 8,247,618–8,271,150, forward strandPFASSLC25A35: 8,287,762–8,295,410, reverse strandSLC25A35RANGRF: 8,288,631–8,290,092, forward strandRANGRFARHGEF15: 8,310,222–8,323,203, forward strandARHGEF15ODF4: 8,339,840–8,346,048, forward strandODF4KRABD2: 8,356,902–8,376,738, reverse strandKRABD2: 8,368,638–8,383,187, reverse strandRPL26: 8,377,500–8,384,062, reverse strandRNF222: 8,390,702–8,397,827, reverse strandRNF222NDEL1: 8,408,528–8,501,107, forward strandNDEL1MYH10: 8,474,205–8,632,303, reverse strandMYH10Diagram of VAMP2: 5 exons on the reverse strand of chromosome 17Exon 3: 2 known disease-causing sitesExon 2: 1 known disease-causing siteExon 5: 8,159,149–8,160,871, 1,723 basesExon 4: 8,161,473–8,161,524, 52 basesExon 3: 8,161,608–8,161,766, 159 basesExon 2: 8,162,249–8,162,369, 121 basesExon 1: 8,162,878–8,162,948, 71 bases543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.1 kb of the gene's 3.8 kb; 351 of those bases code for the protein.

How a genome test reads VAMP2

3

positions in VAMP2 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 3.8 kb of VAMP2, introns included, not only the 2.1 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). VAMP2 gene: vesicle associated membrane protein 2. Retrieved 17 October 2026, from https://dantelabs.com/genes/vamp2

Vancouver

Dante Labs. VAMP2 gene: vesicle associated membrane protein 2 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/vamp2

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