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Gene

TLE5

TLE family member 5, transcriptional modulator

Summary

Cytogenetic location
19p13.3
Coordinates
Chromosome 19: 3,052,910–3,062,495 (GRCh38)
Exons
7 exons across 9.6 kb
Protein
197 amino acids
Also known as
GRG5
Previous symbols
AES
MANE Select transcript
ENST00000327141.9NM_001130.6
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads TLE5 yet. The test sequences your whole genome, so your data includes it all the same.

How TLE5 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 19, with a bracket where TLE5 sits. TLE5 and 25 genes near it on chromosome 19, from 2,557,703 to 3,557,702.Chromosome 1919p13.3p13.3p13.2p13.13p13.12p13.11p12p11q11q12q13.11q13.12q13.13q13.2q13.31q13.32q13.33q13.41q13.42q13.432.6 Mb2.8 Mb3 Mb3.2 Mb3.4 MbGNG7: 2,511,214–2,702,727, reverse strandGNG7DIRAS1: 2,714,566–2,721,438, reverse strandDIRAS1: 2,717,769–2,740,048, reverse strandSLC39A3: 2,732,204–2,740,071, reverse strandSLC39A3SGTA: 2,754,711–2,783,390, reverse strandSGTATHOP1: 2,785,444–2,815,807, forward strandTHOP1ZNF554: 2,819,853–2,836,735, forward strandZNF554ZNF555: 2,841,437–2,860,471, forward strandZNF555ZNF556: 2,867,292–2,883,445, forward strandZNF556ZNF57: 2,900,914–2,919,102, forward strandZNF57ZNF77: 2,931,137–2,944,971, reverse strandZNF77TLE6: 2,977,538–2,995,179, forward strandTLE6TLE2: 2,997,632–3,047,635, reverse strandTLE2TLE5: 3,052,910–3,062,495, reverse strandTLE5GNA11: 3,094,320–3,124,001, forward strandGNA11GNA15: 3,136,027–3,163,749, forward strandGNA15S1PR4: 3,172,346–3,180,332, forward strandS1PR4NCLN: 3,185,563–3,209,575, forward strandNCLNCELF5: 3,224,636–3,297,076, forward strandCELF5NFIC: 3,314,403–3,469,217, forward strandNFICSMIM24: 3,473,986–3,480,557, reverse strandSMIM24SMIM44: 3,482,110–3,483,441, reverse strandSMIM44DOHH: 3,490,821–3,507,203, reverse strandDOHHFZR1: 3,506,270–3,538,334, forward strandFZR1MFSD12: 3,538,261–3,574,290, reverse strandMFSD12TEKTIP1: 3,539,169–3,544,030, forward strandDiagram of TLE5: 7 exons on the reverse strand of chromosome 19Exon 7: 3,052,910–3,054,040, 1,131 basesExon 6: 3,054,120–3,054,194, 75 basesExon 5: 3,055,664–3,055,726, 63 basesExon 4: 3,056,312–3,056,356, 45 basesExon 3: 3,057,679–3,057,742, 64 basesExon 2: 3,061,160–3,061,257, 98 basesExon 1: 3,062,174–3,062,495, 322 bases76543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.8 kb of the gene's 9.6 kb; 594 of those bases code for the protein.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). TLE5 gene: TLE family member 5, transcriptional modulator. Retrieved 17 October 2026, from https://dantelabs.com/genes/tle5

Vancouver

Dante Labs. TLE5 gene: TLE family member 5, transcriptional modulator [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/tle5

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